Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (601 aa)    
Predicted Functional Partners:
FAM53C
Protein FAM53C; Belongs to the FAM53 family.
    
 
 0.972
DYRK1A
DYRK1A isoform 7.
   
    0.889
C10H10orf71
C10orf71 isoform 1.
   
 
 0.806
FAM53B
Family with sequence similarity 53 member B.
    
 
 0.803
FAM53A
Family with sequence similarity 53 member A.
    
 
 0.802
LIN52
Protein lin-52 homolog.
    
 0.772
RNF169
Ring finger protein 169.
   
 
 0.763
EP300
EP300 isoform 1.
   
 0.763
RAD54L2
RAD54L2 isoform 1.
    
 
 0.757
FANCD2OS
FANCD2 opposite strand.
    
   0.742
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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