| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| B4GAT1 | FCGBP | ENSPPYP00000004686 | ENSPPYP00000011172 | Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose- beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O- mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G- like domain-containing extracellular proteins with high affinity. Required fo [...] | FCGBP isoform 1. | 0.647 |
| CD46 | CD9 | ENSPPYP00000000275 | ENSPPYP00000004764 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | Tetraspanin. | 0.441 |
| CD46 | FCGBP | ENSPPYP00000000275 | ENSPPYP00000011172 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | FCGBP isoform 1. | 0.624 |
| CD46 | GAPDHS | ENSPPYP00000000275 | ENSPPYP00000011047 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | Glyceraldehyde-3-phosphate dehydrogenase. | 0.620 |
| CD46 | PARK7 | ENSPPYP00000000275 | ENSPPYP00000002233 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | PARK7 isoform 1. | 0.656 |
| CD9 | CD46 | ENSPPYP00000004764 | ENSPPYP00000000275 | Tetraspanin. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | 0.441 |
| CD9 | FCGBP | ENSPPYP00000004764 | ENSPPYP00000011172 | Tetraspanin. | FCGBP isoform 1. | 0.624 |
| CLCA1 | FCGBP | ENSPPYP00000001377 | ENSPPYP00000011172 | CLCA1 isoform 1. | FCGBP isoform 1. | 0.869 |
| CLCA1 | TFF3 | ENSPPYP00000001377 | ENSPPYP00000012892 | CLCA1 isoform 1. | TFF3 isoform 1. | 0.727 |
| ENSPPYP00000012780 | FCGBP | ENSPPYP00000012780 | ENSPPYP00000011172 | annotation not available | FCGBP isoform 1. | 0.839 |
| FCGBP | B4GAT1 | ENSPPYP00000011172 | ENSPPYP00000004686 | FCGBP isoform 1. | Beta-1,4-glucuronyltransferase 1; Beta-1,4-glucuronyltransferase involved in O-mannosylation of alpha-dystroglycan (DAG1). Transfers a glucuronic acid (GlcA) residue onto a xylose (Xyl) acceptor to produce the glucuronyl-beta-1,4-xylose- beta disaccharide primer, which is further elongated by LARGE1, during synthesis of phosphorylated O-mannosyl glycan. Phosphorylated O- mannosyl glycan is a carbohydrate is a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G- like domain-containing extracellular proteins with high affinity. Required fo [...] | 0.647 |
| FCGBP | CD46 | ENSPPYP00000011172 | ENSPPYP00000000275 | FCGBP isoform 1. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | 0.624 |
| FCGBP | CD9 | ENSPPYP00000011172 | ENSPPYP00000004764 | FCGBP isoform 1. | Tetraspanin. | 0.624 |
| FCGBP | CLCA1 | ENSPPYP00000011172 | ENSPPYP00000001377 | FCGBP isoform 1. | CLCA1 isoform 1. | 0.869 |
| FCGBP | ENSPPYP00000012780 | ENSPPYP00000011172 | ENSPPYP00000012780 | FCGBP isoform 1. | annotation not available | 0.839 |
| FCGBP | GAPDHS | ENSPPYP00000011172 | ENSPPYP00000011047 | FCGBP isoform 1. | Glyceraldehyde-3-phosphate dehydrogenase. | 0.627 |
| FCGBP | PARK7 | ENSPPYP00000011172 | ENSPPYP00000002233 | FCGBP isoform 1. | PARK7 isoform 1. | 0.653 |
| FCGBP | PRM2 | ENSPPYP00000011172 | ENSPPYP00000008032 | FCGBP isoform 1. | PRM2 isoform 2. | 0.753 |
| FCGBP | SEMG2 | ENSPPYP00000011172 | ENSPPYP00000012344 | FCGBP isoform 1. | Semenogelin-2; Participates in the formation of a gel matrix (sperm coagulum) entrapping the accessory gland secretions and ejaculated spermatozoa. | 0.585 |
| FCGBP | TFF3 | ENSPPYP00000011172 | ENSPPYP00000012892 | FCGBP isoform 1. | TFF3 isoform 1. | 0.839 |
