SHKBP1 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BTBD10	CUL3	ENSPPYP00000003985	ENSPPYP00000014786	BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.	CUL3 isoform 1; Belongs to the cullin family.	0.822
BTBD10	KCTD3	ENSPPYP00000003985	ENSPPYP00000000226	BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.	Potassium channel tetramerization domain containing 3.	0.474
BTBD10	SHKBP1	ENSPPYP00000003985	ENSPPYP00000011189	BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.	SHKBP1 isoform 1.	0.605
CUL3	BTBD10	ENSPPYP00000014786	ENSPPYP00000003985	CUL3 isoform 1; Belongs to the cullin family.	BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.	0.822
CUL3	KCTD3	ENSPPYP00000014786	ENSPPYP00000000226	CUL3 isoform 1; Belongs to the cullin family.	Potassium channel tetramerization domain containing 3.	0.779
CUL3	SHKBP1	ENSPPYP00000014786	ENSPPYP00000011189	CUL3 isoform 1; Belongs to the cullin family.	SHKBP1 isoform 1.	0.808
KCTD3	BTBD10	ENSPPYP00000000226	ENSPPYP00000003985	Potassium channel tetramerization domain containing 3.	BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.	0.474
KCTD3	CUL3	ENSPPYP00000000226	ENSPPYP00000014786	Potassium channel tetramerization domain containing 3.	CUL3 isoform 1; Belongs to the cullin family.	0.779
KCTD3	MTM1	ENSPPYP00000000226	ENSPPYP00000023299	Potassium channel tetramerization domain containing 3.	Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...]	0.522
KCTD3	PIH1D1	ENSPPYP00000000226	ENSPPYP00000011473	Potassium channel tetramerization domain containing 3.	PIH1 domain containing 1.	0.634
KCTD3	PUS3	ENSPPYP00000000226	ENSPPYP00000004618	Potassium channel tetramerization domain containing 3.	Pseudouridine synthase 3.	0.465
KCTD3	SHKBP1	ENSPPYP00000000226	ENSPPYP00000011189	Potassium channel tetramerization domain containing 3.	SHKBP1 isoform 1.	0.922
KCTD3	SNX27	ENSPPYP00000000226	ENSPPYP00000001005	Potassium channel tetramerization domain containing 3.	SNX27 isoform 2.	0.482
KCTD3	TNFAIP3	ENSPPYP00000000226	ENSPPYP00000019084	Potassium channel tetramerization domain containing 3.	TNFAIP3 isoform 1.	0.558
MTM1	KCTD3	ENSPPYP00000023299	ENSPPYP00000000226	Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...]	Potassium channel tetramerization domain containing 3.	0.522
MTM1	PUS3	ENSPPYP00000023299	ENSPPYP00000004618	Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...]	Pseudouridine synthase 3.	0.614
MTM1	SHKBP1	ENSPPYP00000023299	ENSPPYP00000011189	Myotubularin; Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not fo [...]	SHKBP1 isoform 1.	0.669
PIH1D1	KCTD3	ENSPPYP00000011473	ENSPPYP00000000226	PIH1 domain containing 1.	Potassium channel tetramerization domain containing 3.	0.634
PIH1D1	SHKBP1	ENSPPYP00000011473	ENSPPYP00000011189	PIH1 domain containing 1.	SHKBP1 isoform 1.	0.634
PUS3	KCTD3	ENSPPYP00000004618	ENSPPYP00000000226	Pseudouridine synthase 3.	Potassium channel tetramerization domain containing 3.	0.465