DMPK protein (Pongo abelii) - STRING interaction network

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Score

DMPK

DM1 protein kinase. (629 aa)

Predicted Functional Partners:

CDC42

0.759

MBNL1

0.719

CELF1

0.644

PPP1R12A

0.642

RHOQ

0.636

MBNL2

0.623

MID2

0.617

TRIM9

0.614

CR201_G0022704

0.609

MBNL3

0.586

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC42	DMPK	ENSPPYP00000002031	ENSPPYP00000011331	Cell division cycle 42.	DM1 protein kinase.	0.759
CDC42	PPP1R12A	ENSPPYP00000002031	ENSPPYP00000005469	Cell division cycle 42.	Protein phosphatase 1 regulatory subunit.	0.504
CDC42	RHOQ	ENSPPYP00000002031	ENSPPYP00000013889	Cell division cycle 42.	RHOQ isoform 1.	0.496
CELF1	CR201_G0022704	ENSPPYP00000003787	ENSPPYP00000020324	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	CLCN1 isoform 2.	0.629
CELF1	DMPK	ENSPPYP00000003787	ENSPPYP00000011331	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	DM1 protein kinase.	0.644
CELF1	MBNL1	ENSPPYP00000003787	ENSPPYP00000015898	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	Muscleblind like splicing regulator 1.	0.884
CELF1	MBNL2	ENSPPYP00000003787	ENSPPYP00000006216	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	Muscleblind-like protein 2; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expr [...]	0.646
CELF1	MBNL3	ENSPPYP00000003787	ENSPPYP00000023203	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	Muscleblind like splicing regulator 3.	0.699
CR201_G0022704	CELF1	ENSPPYP00000020324	ENSPPYP00000003787	CLCN1 isoform 2.	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	0.629
CR201_G0022704	DMPK	ENSPPYP00000020324	ENSPPYP00000011331	CLCN1 isoform 2.	DM1 protein kinase.	0.609
CR201_G0022704	MBNL1	ENSPPYP00000020324	ENSPPYP00000015898	CLCN1 isoform 2.	Muscleblind like splicing regulator 1.	0.688
CR201_G0022704	MBNL2	ENSPPYP00000020324	ENSPPYP00000006216	CLCN1 isoform 2.	Muscleblind-like protein 2; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expr [...]	0.655
CR201_G0022704	MBNL3	ENSPPYP00000020324	ENSPPYP00000023203	CLCN1 isoform 2.	Muscleblind like splicing regulator 3.	0.636
DMPK	CDC42	ENSPPYP00000011331	ENSPPYP00000002031	DM1 protein kinase.	Cell division cycle 42.	0.759
DMPK	CELF1	ENSPPYP00000011331	ENSPPYP00000003787	DM1 protein kinase.	CUGBP Elav-like family member 1; RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts as both an activator and repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon bu [...]	0.644
DMPK	CR201_G0022704	ENSPPYP00000011331	ENSPPYP00000020324	DM1 protein kinase.	CLCN1 isoform 2.	0.609
DMPK	MBNL1	ENSPPYP00000011331	ENSPPYP00000015898	DM1 protein kinase.	Muscleblind like splicing regulator 1.	0.719
DMPK	MBNL2	ENSPPYP00000011331	ENSPPYP00000006216	DM1 protein kinase.	Muscleblind-like protein 2; Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T (TNNT2) pre-mRNA exon inclusion but induces insulin receptor (IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. RNA-binding protein that binds to 5'ACACCC-3' core sequence, termed zipcode, within the 3'UTR of ITGA3. Binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. Seems to regulate expr [...]	0.623
DMPK	MBNL3	ENSPPYP00000011331	ENSPPYP00000023203	DM1 protein kinase.	Muscleblind like splicing regulator 3.	0.586
DMPK	MID2	ENSPPYP00000011331	ENSPPYP00000023076	DM1 protein kinase.	MID2 isoform 2.	0.617