STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACP4Acid phosphatase 4; Belongs to the histidine acid phosphatase family. (425 aa)    
Predicted Functional Partners:
RXFP4
RXFP4 isoform 1.
     
 0.802
DSG4
DSG4 isoform 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
      
 0.798
TGM5
Transglutaminase 5.
      
 0.796
ACOX2
Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.
      
 0.791
KLK8
Kallikrein related peptidase 8; Belongs to the peptidase S1 family.
    
 
 0.778
ADAMTS20
ADAMTS20 isoform 1.
   
  
 0.616
UPP1
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
      
 0.577
GNAT2
G protein subunit alpha transducin 2.
      
 0.576
ABCB4
ABCB4 isoform 3.
      
 0.576
TBX22
T-box transcription factor 22.
      
 0.575
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.