| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CASP1 | MEFV | ENSPPYP00000004375 | ENSPPYP00000007958 | CASP1 isoform 4; Belongs to the peptidase C14A family. | MEFV isoform 4. | 0.992 |
| CASP1 | NLRC4 | ENSPPYP00000004375 | ENSPPYP00000013968 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRC4 isoform 1. | 0.996 |
| CASP1 | NLRP2 | ENSPPYP00000004375 | ENSPPYP00000011655 | CASP1 isoform 4; Belongs to the peptidase C14A family. | NLRP2 isoform 2. | 0.458 |
| CASP1 | PYCARD | ENSPPYP00000004375 | ENSPPYP00000008260 | CASP1 isoform 4; Belongs to the peptidase C14A family. | PYD and CARD domain containing. | 0.999 |
| CASP1 | RIPK2 | ENSPPYP00000004375 | ENSPPYP00000021009 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.637 |
| CASP1 | TXNIP | ENSPPYP00000004375 | ENSPPYP00000001080 | CASP1 isoform 4; Belongs to the peptidase C14A family. | Thioredoxin-interacting protein; May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1) (By similarity). Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and co [...] | 0.475 |
| CR201_G0031170-2 | NLRP2 | ENSPPYP00000018933 | ENSPPYP00000011655 | AK9 isoform 9. | NLRP2 isoform 2. | 0.623 |
| MAVS | NLRP2 | ENSPPYP00000012072 | ENSPPYP00000011655 | MAVS isoform 2. | NLRP2 isoform 2. | 0.501 |
| MAVS | PYCARD | ENSPPYP00000012072 | ENSPPYP00000008260 | MAVS isoform 2. | PYD and CARD domain containing. | 0.420 |
| MAVS | RIPK2 | ENSPPYP00000012072 | ENSPPYP00000021009 | MAVS isoform 2. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.643 |
| MAVS | SYNGR1 | ENSPPYP00000012072 | ENSPPYP00000013210 | MAVS isoform 2. | Synaptogyrin-1; May play a role in regulated exocytosis. Modulates the localization of synaptophysin/SYP into synaptic-like microvesicles and may therefore play a role in synaptic-like microvesicle formation and/or maturation (By similarity). Involved in the regulation of short- term and long-term synaptic plasticity (By similarity). Belongs to the synaptogyrin family. | 0.914 |
| MEFV | CASP1 | ENSPPYP00000007958 | ENSPPYP00000004375 | MEFV isoform 4. | CASP1 isoform 4; Belongs to the peptidase C14A family. | 0.992 |
| MEFV | NLRC4 | ENSPPYP00000007958 | ENSPPYP00000013968 | MEFV isoform 4. | NLRC4 isoform 1. | 0.759 |
| MEFV | NLRP2 | ENSPPYP00000007958 | ENSPPYP00000011655 | MEFV isoform 4. | NLRP2 isoform 2. | 0.468 |
| MEFV | PYCARD | ENSPPYP00000007958 | ENSPPYP00000008260 | MEFV isoform 4. | PYD and CARD domain containing. | 0.995 |
| NLRC4 | CASP1 | ENSPPYP00000013968 | ENSPPYP00000004375 | NLRC4 isoform 1. | CASP1 isoform 4; Belongs to the peptidase C14A family. | 0.996 |
| NLRC4 | MEFV | ENSPPYP00000013968 | ENSPPYP00000007958 | NLRC4 isoform 1. | MEFV isoform 4. | 0.759 |
| NLRC4 | NLRP2 | ENSPPYP00000013968 | ENSPPYP00000011655 | NLRC4 isoform 1. | NLRP2 isoform 2. | 0.445 |
| NLRC4 | PYCARD | ENSPPYP00000013968 | ENSPPYP00000008260 | NLRC4 isoform 1. | PYD and CARD domain containing. | 0.992 |
| NLRC4 | RIPK2 | ENSPPYP00000013968 | ENSPPYP00000021009 | NLRC4 isoform 1. | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. | 0.490 |
