| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALYREF | CR201_G0029379 | ENSPPYP00000009820 | ENSPPYP00000012799 | Aly/REF export factor. | U2AF1L5 isoform 2. | 0.623 |
| ALYREF | RBM10 | ENSPPYP00000009820 | ENSPPYP00000022703 | Aly/REF export factor. | RBM10 isoform 4. | 0.414 |
| ALYREF | SF3A2 | ENSPPYP00000009820 | ENSPPYP00000010484 | Aly/REF export factor. | SF3A2 isoform 1. | 0.726 |
| ALYREF | SNRPA | ENSPPYP00000009820 | ENSPPYP00000011196 | Aly/REF export factor. | Small nuclear ribonucleoprotein polypeptide A. | 0.438 |
| ALYREF | SRSF1 | ENSPPYP00000009820 | ENSPPYP00000024624 | Aly/REF export factor. | Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] | 0.990 |
| ALYREF | SRSF3 | ENSPPYP00000009820 | ENSPPYP00000018510 | Aly/REF export factor. | SRSF3 isoform 5. | 0.955 |
| ALYREF | SRSF5 | ENSPPYP00000009820 | ENSPPYP00000006761 | Aly/REF export factor. | Serine and arginine rich splicing factor 5. | 0.927 |
| ALYREF | U2AF2 | ENSPPYP00000009820 | ENSPPYP00000011687 | Aly/REF export factor. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.977 |
| CR201_G0029379 | ALYREF | ENSPPYP00000012799 | ENSPPYP00000009820 | U2AF1L5 isoform 2. | Aly/REF export factor. | 0.623 |
| CR201_G0029379 | JMJD6 | ENSPPYP00000012799 | ENSPPYP00000009734 | U2AF1L5 isoform 2. | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5- hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5- hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by it [...] | 0.538 |
| CR201_G0029379 | RBM10 | ENSPPYP00000012799 | ENSPPYP00000022703 | U2AF1L5 isoform 2. | RBM10 isoform 4. | 0.726 |
| CR201_G0029379 | SF3A2 | ENSPPYP00000012799 | ENSPPYP00000010484 | U2AF1L5 isoform 2. | SF3A2 isoform 1. | 0.849 |
| CR201_G0029379 | SNRPA | ENSPPYP00000012799 | ENSPPYP00000011196 | U2AF1L5 isoform 2. | Small nuclear ribonucleoprotein polypeptide A. | 0.551 |
| CR201_G0029379 | SRSF1 | ENSPPYP00000012799 | ENSPPYP00000024624 | U2AF1L5 isoform 2. | Serine/arginine-rich splicing factor 1; Plays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5'-splice site- containing pre-mRNA. Binds to purine-rich RNA sequences, either the octamer, 5'-RGAAGAAC-3' (r=A or G) or the decamers, AGGACAGAGC/AGGACGAAGC. Binds preferentially to the 5'-CGAGGCG-3' motif in vitro. Three copies of the octame [...] | 0.945 |
| CR201_G0029379 | SRSF3 | ENSPPYP00000012799 | ENSPPYP00000018510 | U2AF1L5 isoform 2. | SRSF3 isoform 5. | 0.831 |
| CR201_G0029379 | SRSF5 | ENSPPYP00000012799 | ENSPPYP00000006761 | U2AF1L5 isoform 2. | Serine and arginine rich splicing factor 5. | 0.726 |
| CR201_G0029379 | SUGP1 | ENSPPYP00000012799 | ENSPPYP00000010938 | U2AF1L5 isoform 2. | SUGP1 isoform 1. | 0.509 |
| CR201_G0029379 | U2AF2 | ENSPPYP00000012799 | ENSPPYP00000011687 | U2AF1L5 isoform 2. | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.997 |
| JMJD6 | CR201_G0029379 | ENSPPYP00000009734 | ENSPPYP00000012799 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5- hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5- hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by it [...] | U2AF1L5 isoform 2. | 0.538 |
| JMJD6 | U2AF2 | ENSPPYP00000009734 | ENSPPYP00000011687 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6; Dioxygenase that can both act as a arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5- hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Regulates RNA splicing by mediating 5- hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. Hydroxylates its own N-terminus, which is required for homooligomerization. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by it [...] | U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. | 0.966 |
