| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C3AR1 | C4BPA | ENSPPYP00000004833 | ENSPPYP00000000285 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C4BPA isoform 1. | 0.601 |
| C3AR1 | C5 | ENSPPYP00000004833 | ENSPPYP00000021918 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C5 isoform 1. | 0.972 |
| C3AR1 | C5AR2 | ENSPPYP00000004833 | ENSPPYP00000011375 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | C5a anaphylatoxin chemotactic receptor 2. | 0.434 |
| C3AR1 | CD46 | ENSPPYP00000004833 | ENSPPYP00000000275 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | 0.412 |
| C3AR1 | CD55 | ENSPPYP00000004833 | ENSPPYP00000000283 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | CD55 isoform 4. | 0.597 |
| C3AR1 | ENSPPYP00000011804 | ENSPPYP00000004833 | ENSPPYP00000011804 | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | LOW QUALITY PROTEIN: putative protein C3P1. | 0.769 |
| C4BPA | C3AR1 | ENSPPYP00000000285 | ENSPPYP00000004833 | C4BPA isoform 1. | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.601 |
| C4BPA | C5 | ENSPPYP00000000285 | ENSPPYP00000021918 | C4BPA isoform 1. | C5 isoform 1. | 0.635 |
| C4BPA | CD46 | ENSPPYP00000000285 | ENSPPYP00000000275 | C4BPA isoform 1. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | 0.925 |
| C4BPA | CFI | ENSPPYP00000000285 | ENSPPYP00000016746 | C4BPA isoform 1. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.920 |
| C4BPA | ENSPPYP00000011804 | ENSPPYP00000000285 | ENSPPYP00000011804 | C4BPA isoform 1. | LOW QUALITY PROTEIN: putative protein C3P1. | 0.632 |
| C5 | C3AR1 | ENSPPYP00000021918 | ENSPPYP00000004833 | C5 isoform 1. | C3a anaphylatoxin chemotactic receptor; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C3a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.972 |
| C5 | C4BPA | ENSPPYP00000021918 | ENSPPYP00000000285 | C5 isoform 1. | C4BPA isoform 1. | 0.635 |
| C5 | C5AR2 | ENSPPYP00000021918 | ENSPPYP00000011375 | C5 isoform 1. | C5a anaphylatoxin chemotactic receptor 2. | 0.989 |
| C5 | CD46 | ENSPPYP00000021918 | ENSPPYP00000000275 | C5 isoform 1. | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | 0.558 |
| C5 | CD55 | ENSPPYP00000021918 | ENSPPYP00000000283 | C5 isoform 1. | CD55 isoform 4. | 0.543 |
| C5 | CFHR2 | ENSPPYP00000021918 | ENSPPYP00000000442 | C5 isoform 1. | Complement factor H related 2. | 0.585 |
| C5 | CFI | ENSPPYP00000021918 | ENSPPYP00000016746 | C5 isoform 1. | Complement factor I heavy chain; Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively. | 0.812 |
| C5 | ENSPPYP00000011804 | ENSPPYP00000021918 | ENSPPYP00000011804 | C5 isoform 1. | LOW QUALITY PROTEIN: putative protein C3P1. | 0.645 |
| C5 | MASP2 | ENSPPYP00000021918 | ENSPPYP00000002193 | C5 isoform 1. | MASP2 isoform 1; Belongs to the peptidase S1 family. | 0.589 |
