| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CD46 | JAG1 | ENSPPYP00000000275 | ENSPPYP00000011973 | Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity (By similarity). | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.762 |
| ENSPPYP00000018736 | ENSPPYP00000018738 | ENSPPYP00000018736 | ENSPPYP00000018738 | annotation not available | annotation not available | 0.486 |
| ENSPPYP00000018736 | ENSPPYP00000018739 | ENSPPYP00000018736 | ENSPPYP00000018739 | annotation not available | annotation not available | 0.896 |
| ENSPPYP00000018736 | JAG1 | ENSPPYP00000018736 | ENSPPYP00000011973 | annotation not available | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.743 |
| ENSPPYP00000018736 | NOTCH1 | ENSPPYP00000018736 | ENSPPYP00000022176 | annotation not available | NOTCH1 isoform 1. | 0.508 |
| ENSPPYP00000018736 | NOTCH3 | ENSPPYP00000018736 | ENSPPYP00000010835 | annotation not available | NOTCH3 isoform 1. | 0.586 |
| ENSPPYP00000018736 | NOTCH4 | ENSPPYP00000018736 | ENSPPYP00000018437 | annotation not available | NOTCH4 isoform 1. | 0.683 |
| ENSPPYP00000018738 | ENSPPYP00000018736 | ENSPPYP00000018738 | ENSPPYP00000018736 | annotation not available | annotation not available | 0.486 |
| ENSPPYP00000018738 | ENSPPYP00000018739 | ENSPPYP00000018738 | ENSPPYP00000018739 | annotation not available | annotation not available | 0.734 |
| ENSPPYP00000018738 | EYS | ENSPPYP00000018738 | ENSPPYP00000018737 | annotation not available | EYS isoform 3. | 0.478 |
| ENSPPYP00000018738 | JAG1 | ENSPPYP00000018738 | ENSPPYP00000011973 | annotation not available | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.743 |
| ENSPPYP00000018738 | NOTCH1 | ENSPPYP00000018738 | ENSPPYP00000022176 | annotation not available | NOTCH1 isoform 1. | 0.508 |
| ENSPPYP00000018738 | NOTCH3 | ENSPPYP00000018738 | ENSPPYP00000010835 | annotation not available | NOTCH3 isoform 1. | 0.586 |
| ENSPPYP00000018738 | NOTCH4 | ENSPPYP00000018738 | ENSPPYP00000018437 | annotation not available | NOTCH4 isoform 1. | 0.683 |
| ENSPPYP00000018739 | ENSPPYP00000018736 | ENSPPYP00000018739 | ENSPPYP00000018736 | annotation not available | annotation not available | 0.896 |
| ENSPPYP00000018739 | ENSPPYP00000018738 | ENSPPYP00000018739 | ENSPPYP00000018738 | annotation not available | annotation not available | 0.734 |
| ENSPPYP00000018739 | EYS | ENSPPYP00000018739 | ENSPPYP00000018737 | annotation not available | EYS isoform 3. | 0.893 |
| ENSPPYP00000018739 | JAG1 | ENSPPYP00000018739 | ENSPPYP00000011973 | annotation not available | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. | 0.955 |
| ENSPPYP00000018739 | NOTCH3 | ENSPPYP00000018739 | ENSPPYP00000010835 | annotation not available | NOTCH3 isoform 1. | 0.843 |
| ENSPPYP00000018739 | NOTCH4 | ENSPPYP00000018739 | ENSPPYP00000018437 | annotation not available | NOTCH4 isoform 1. | 0.796 |
