DSTN protein (Pongo abelii) - STRING interaction network

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Predicted Interactions

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Score

DSTN

Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family. (165 aa)

Predicted Functional Partners:

ACTG1

0.880

ACTB

0.880

CFL2

0.866

LIMK1

0.684

TWF1

0.671

CR201_G0024533

0.635

PFN1

0.620

PFN3

0.608

PFN4

0.606

WDR1

0.595

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	ACTG1	ENSPPYP00000019427	ENSPPYP00000009805	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	ACTG1 isoform 10.	0.999
ACTB	CFL2	ENSPPYP00000019427	ENSPPYP00000006519	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	0.992
ACTB	DSTN	ENSPPYP00000019427	ENSPPYP00000011991	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.880
ACTB	PFN1	ENSPPYP00000019427	ENSPPYP00000008839	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Profilin; Belongs to the profilin family.	0.988
ACTB	PFN3	ENSPPYP00000019427	ENSPPYP00000018006	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Profilin; Belongs to the profilin family.	0.986
ACTB	PFN4	ENSPPYP00000019427	ENSPPYP00000014071	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Profilin; Belongs to the profilin family.	0.989
ACTB	TWF1	ENSPPYP00000019427	ENSPPYP00000005055	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.	0.453
ACTB	WDR1	ENSPPYP00000019427	ENSPPYP00000016318	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	WDR1 isoform 1.	0.606
ACTG1	ACTB	ENSPPYP00000009805	ENSPPYP00000019427	ACTG1 isoform 10.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.999
ACTG1	CFL2	ENSPPYP00000009805	ENSPPYP00000006519	ACTG1 isoform 10.	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	0.989
ACTG1	DSTN	ENSPPYP00000009805	ENSPPYP00000011991	ACTG1 isoform 10.	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.880
ACTG1	PFN1	ENSPPYP00000009805	ENSPPYP00000008839	ACTG1 isoform 10.	Profilin; Belongs to the profilin family.	0.821
ACTG1	PFN3	ENSPPYP00000009805	ENSPPYP00000018006	ACTG1 isoform 10.	Profilin; Belongs to the profilin family.	0.976
ACTG1	PFN4	ENSPPYP00000009805	ENSPPYP00000014071	ACTG1 isoform 10.	Profilin; Belongs to the profilin family.	0.980
ACTG1	TWF1	ENSPPYP00000009805	ENSPPYP00000005055	ACTG1 isoform 10.	Twinfilin-1; Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles (By similarity). Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.	0.453
ACTG1	WDR1	ENSPPYP00000009805	ENSPPYP00000016318	ACTG1 isoform 10.	WDR1 isoform 1.	0.606
CFL2	ACTB	ENSPPYP00000006519	ENSPPYP00000019427	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.992
CFL2	ACTG1	ENSPPYP00000006519	ENSPPYP00000009805	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	ACTG1 isoform 10.	0.989
CFL2	CR201_G0024533	ENSPPYP00000006519	ENSPPYP00000013085	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	LIMK2 isoform 3.	0.839
CFL2	DSTN	ENSPPYP00000006519	ENSPPYP00000011991	CFL2 isoform 1; Belongs to the actin-binding proteins ADF family.	Destrin, actin depolymerizing factor; Belongs to the actin-binding proteins ADF family.	0.866