STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RALGAPA2RALGAPA2 isoform 2. (1921 aa)    
Predicted Functional Partners:
RALGAPB
RALGAPB isoform 1.
   
0.997
RALA
RAS like proto-oncogene A.
   
 0.964
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.954
RALB
Ras-related protein Ral-B; Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles (By similarity). Required both to stabilize the assembly of the exocyst complex and to localize functional exocyst complexes to the leading edge of migrating cells (By similarity). Required for suppression of apoptosis (By s [...]
   
 0.941
NKIRAS2
NFKB inhibitor interacting Ras like 2.
    
 
 0.933
AKT3
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.926
AKT1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
  0.926
GFOD1
Glucose-fructose oxidoreductase domain containing 1.
    
   0.915
NKIRAS1
NFKB inhibitor interacting Ras like 1.
    
 
 0.794
ICA1
ICA1 isoform 12.
      
 0.617
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.