STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDC4Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP; Belongs to the syndecan proteoglycan family (198 aa)    
Predicted Functional Partners:
SDCBP
Uncharacterized protein DKFZp459H1728; Pongo abelii syndecan binding protein (syntenin) (SDCBP), mRNA
    
 
 0.986
FN1
Fibronectin 1
   
 0.950
GPC1
Glypican 1; Cell surface proteoglycan that bears heparan sulfate
   
 
 0.910
PXN
Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion); Belongs to the paxillin family
    
 0.863
SDC1
Syndecan; Cell surface proteoglycan
   
0.849
SDC2
Syndecan; Cell surface proteoglycan
   
0.849
NUDT16L1
Nudix hydrolase 16 like 1; Nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
     
 0.846
TNC
Tenascin C
   
 
 0.846
TNN
Tenascin N
     
 0.836
THBS1
Thrombospondin 1
   
 
 0.834
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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