STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (529 aa)    
Predicted Functional Partners:
SIX1
SIX homeobox 1.
   
 0.960
SIX2
SIX homeobox 2.
   
 0.894
SIX4
SIX4 isoform 1.
   
 0.767
SIX5
SIX5 isoform 1.
   
 0.675
MEGF11
MEGF11 isoform 1.
      
 0.665
DACH1
DACH1 isoform 3.
    
 
 0.647
MPZL3
Myelin protein zero like 3.
      
 0.628
RHBDF1
Rhomboid 5 homolog 1.
      
 0.628
WSCD2
WSC domain containing 2.
      
 0.627
PHACTR1
Phosphatase and actin regulator.
      
 0.605
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.