CEBPB protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATF4	CEBPB	ENSPPYP00000013213	ENSPPYP00000012431	ATF4 isoform 1.	CCAAT/enhancer-binding protein.	0.906
ATF4	CEBPG	ENSPPYP00000013213	ENSPPYP00000011005	ATF4 isoform 1.	CEBPG isoform 1.	0.964
ATF4	DDIT3	ENSPPYP00000013213	ENSPPYP00000005345	ATF4 isoform 1.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.994
ATF4	GSK3B	ENSPPYP00000013213	ENSPPYP00000015105	ATF4 isoform 1.	GSK3B isoform 2; Belongs to the protein kinase superfamily.	0.911
ATF4	MAPK3	ENSPPYP00000013213	ENSPPYP00000008184	ATF4 isoform 1.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.915
CEBPB	ATF4	ENSPPYP00000012431	ENSPPYP00000013213	CCAAT/enhancer-binding protein.	ATF4 isoform 1.	0.906
CEBPB	CEBPG	ENSPPYP00000012431	ENSPPYP00000011005	CCAAT/enhancer-binding protein.	CEBPG isoform 1.	0.963
CEBPB	DDIT3	ENSPPYP00000012431	ENSPPYP00000005345	CCAAT/enhancer-binding protein.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.916
CEBPB	GSK3B	ENSPPYP00000012431	ENSPPYP00000015105	CCAAT/enhancer-binding protein.	GSK3B isoform 2; Belongs to the protein kinase superfamily.	0.925
CEBPB	MAPK12	ENSPPYP00000012431	ENSPPYP00000013363	CCAAT/enhancer-binding protein.	Mitogen-activated protein kinase.	0.944
CEBPB	MAPK13	ENSPPYP00000012431	ENSPPYP00000018501	CCAAT/enhancer-binding protein.	Mitogen-activated protein kinase.	0.944
CEBPB	MAPK14	ENSPPYP00000012431	ENSPPYP00000018500	CCAAT/enhancer-binding protein.	Mitogen-activated protein kinase.	0.949
CEBPB	MAPK3	ENSPPYP00000012431	ENSPPYP00000008184	CCAAT/enhancer-binding protein.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.972
CEBPB	RELA	ENSPPYP00000012431	ENSPPYP00000003533	CCAAT/enhancer-binding protein.	RELA proto-oncogene, NF-kB subunit.	0.943
CEBPB	TRAF6	ENSPPYP00000012431	ENSPPYP00000003845	CCAAT/enhancer-binding protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.907
CEBPG	ATF4	ENSPPYP00000011005	ENSPPYP00000013213	CEBPG isoform 1.	ATF4 isoform 1.	0.964
CEBPG	CEBPB	ENSPPYP00000011005	ENSPPYP00000012431	CEBPG isoform 1.	CCAAT/enhancer-binding protein.	0.963
CEBPG	DDIT3	ENSPPYP00000011005	ENSPPYP00000005345	CEBPG isoform 1.	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	0.901
DDIT3	ATF4	ENSPPYP00000005345	ENSPPYP00000013213	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	ATF4 isoform 1.	0.994
DDIT3	CEBPB	ENSPPYP00000005345	ENSPPYP00000012431	DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...]	CCAAT/enhancer-binding protein.	0.916