| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARID4B | CHD4 | ENSPPYP00000000098 | ENSPPYP00000004777 | AT-rich interaction domain 4B. | CHD4 isoform 1. | 0.612 |
| ARID4B | GATAD2B | ENSPPYP00000000098 | ENSPPYP00000024238 | AT-rich interaction domain 4B. | GATAD2B isoform 2. | 0.449 |
| ARID4B | HDAC1 | ENSPPYP00000000098 | ENSPPYP00000001838 | AT-rich interaction domain 4B. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.929 |
| ARID4B | RBBP4 | ENSPPYP00000000098 | ENSPPYP00000001831 | AT-rich interaction domain 4B. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.951 |
| ARID4B | SALL4 | ENSPPYP00000000098 | ENSPPYP00000012445 | AT-rich interaction domain 4B. | SALL4 isoform 1. | 0.919 |
| CHD4 | ARID4B | ENSPPYP00000004777 | ENSPPYP00000000098 | CHD4 isoform 1. | AT-rich interaction domain 4B. | 0.612 |
| CHD4 | ENSPPYP00000005886 | ENSPPYP00000004777 | ENSPPYP00000005886 | CHD4 isoform 1. | annotation not available | 0.467 |
| CHD4 | GATAD2B | ENSPPYP00000004777 | ENSPPYP00000024238 | CHD4 isoform 1. | GATAD2B isoform 2. | 0.986 |
| CHD4 | HDAC1 | ENSPPYP00000004777 | ENSPPYP00000001838 | CHD4 isoform 1. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.995 |
| CHD4 | LOC100432049 | ENSPPYP00000004777 | ENSPPYP00000004826 | CHD4 isoform 1. | NANOG isoform 2. | 0.467 |
| CHD4 | POU5F1 | ENSPPYP00000004777 | ENSPPYP00000019279 | CHD4 isoform 1. | POU domain protein. | 0.804 |
| CHD4 | RBBP4 | ENSPPYP00000004777 | ENSPPYP00000001831 | CHD4 isoform 1. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.991 |
| CHD4 | SALL4 | ENSPPYP00000004777 | ENSPPYP00000012445 | CHD4 isoform 1. | SALL4 isoform 1. | 0.864 |
| CHD4 | SOX2 | ENSPPYP00000004777 | ENSPPYP00000016027 | CHD4 isoform 1. | SRY-box transcription factor 2. | 0.460 |
| CRBN | SALL4 | ENSPPYP00000015323 | ENSPPYP00000012445 | Protein cereblon; Substrate recognition component of a DCX (DDB1-CUL4-X-box) E3 protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Normal degradation of key regulatory proteins is required for normal limb outgrowth and expression of the fibroblast growth factor FGF8 (By similarity). May play a role in memory and learning by regulating the assembly and neuronal surface expression of large-conductance calcium-activated potassium channels in brain regions involved in memory and learning via its interaction with KCNT1 (By simi [...] | SALL4 isoform 1. | 0.956 |
| ENSPPYP00000005886 | CHD4 | ENSPPYP00000005886 | ENSPPYP00000004777 | annotation not available | CHD4 isoform 1. | 0.467 |
| ENSPPYP00000005886 | GATAD2B | ENSPPYP00000005886 | ENSPPYP00000024238 | annotation not available | GATAD2B isoform 2. | 0.435 |
| ENSPPYP00000005886 | HDAC1 | ENSPPYP00000005886 | ENSPPYP00000001838 | annotation not available | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.516 |
| ENSPPYP00000005886 | POU5F1 | ENSPPYP00000005886 | ENSPPYP00000019279 | annotation not available | POU domain protein. | 0.953 |
| ENSPPYP00000005886 | SALL4 | ENSPPYP00000005886 | ENSPPYP00000012445 | annotation not available | SALL4 isoform 1. | 0.923 |
