RAB22A protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL2	ENSPPYP00000008720	ENSPPYP00000005592	ENSPPYP00000008720	APPL2 isoform 1.	annotation not available	0.762
APPL2	RAB22A	ENSPPYP00000005592	ENSPPYP00000012479	APPL2 isoform 1.	RAB22A, member RAS oncogene family.	0.831
APPL2	RAB31	ENSPPYP00000005592	ENSPPYP00000010107	APPL2 isoform 1.	RAB31, member RAS oncogene family.	0.762
APPL2	RBSN	ENSPPYP00000005592	ENSPPYP00000014998	APPL2 isoform 1.	Rabenosyn, RAB effector.	0.476
CR201_G0021153	ENSPPYP00000008720	ENSPPYP00000009814	ENSPPYP00000008720	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	annotation not available	0.631
CR201_G0021153	RAB22A	ENSPPYP00000009814	ENSPPYP00000012479	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	RAB22A, member RAS oncogene family.	0.827
CR201_G0021153	RAB31	ENSPPYP00000009814	ENSPPYP00000010107	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	RAB31, member RAS oncogene family.	0.711
CR201_G0021153	RBSN	ENSPPYP00000009814	ENSPPYP00000014998	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Rabenosyn, RAB effector.	0.864
CR201_G0021153	STAM	ENSPPYP00000009814	ENSPPYP00000002467	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	Signal transducing adaptor molecule.	0.997
ENSPPYP00000008720	APPL2	ENSPPYP00000008720	ENSPPYP00000005592	annotation not available	APPL2 isoform 1.	0.762
ENSPPYP00000008720	CR201_G0021153	ENSPPYP00000008720	ENSPPYP00000009814	annotation not available	Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...]	0.631
ENSPPYP00000008720	GDI1	ENSPPYP00000008720	ENSPPYP00000023371	annotation not available	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.684
ENSPPYP00000008720	GDI2	ENSPPYP00000008720	ENSPPYP00000002386	annotation not available	Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.	0.684
ENSPPYP00000008720	RAB22A	ENSPPYP00000008720	ENSPPYP00000012479	annotation not available	RAB22A, member RAS oncogene family.	0.832
ENSPPYP00000008720	RABGEF1	ENSPPYP00000008720	ENSPPYP00000019637	annotation not available	RABGEF1 isoform 2.	0.855
ENSPPYP00000008720	RABGGTA	ENSPPYP00000008720	ENSPPYP00000006478	annotation not available	Geranylgeranyl transferase type-2 subunit alpha; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A; Belongs to the protein prenyltransferase subunit alpha family.	0.883
ENSPPYP00000008720	RBSN	ENSPPYP00000008720	ENSPPYP00000014998	annotation not available	Rabenosyn, RAB effector.	0.704
ENSPPYP00000008720	STAM	ENSPPYP00000008720	ENSPPYP00000002467	annotation not available	Signal transducing adaptor molecule.	0.550
GDI1	ENSPPYP00000008720	ENSPPYP00000023371	ENSPPYP00000008720	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	annotation not available	0.684
GDI1	GDI2	ENSPPYP00000023371	ENSPPYP00000002386	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Rab GDP dissociation inhibitor beta; Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.	0.994