RAB22A protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

RAB22A

RAB22A, member RAS oncogene family. (194 aa)

Predicted Functional Partners:

RAB31

0.985

RABGEF1

0.963

RBSN

0.899

GDI1

0.863

APPL2

0.788

APPL1

0.788

RABEP1

0.713

GAK

0.703

RAD51AP1

0.672

RABGGTA

0.670

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APPL1	APPL2	ENSPPYP00000015409	ENSPPYP00000005592	APPL1 isoform 1.	APPL2 isoform 1.	0.928
APPL1	RAB22A	ENSPPYP00000015409	ENSPPYP00000012479	APPL1 isoform 1.	RAB22A, member RAS oncogene family.	0.788
APPL1	RAB31	ENSPPYP00000015409	ENSPPYP00000010107	APPL1 isoform 1.	RAB31, member RAS oncogene family.	0.788
APPL1	RABEP1	ENSPPYP00000015409	ENSPPYP00000008856	APPL1 isoform 1.	Rabaptin, RAB GTPase binding effector protein 1.	0.456
APPL1	RBSN	ENSPPYP00000015409	ENSPPYP00000014998	APPL1 isoform 1.	Rabenosyn, RAB effector.	0.489
APPL2	APPL1	ENSPPYP00000005592	ENSPPYP00000015409	APPL2 isoform 1.	APPL1 isoform 1.	0.928
APPL2	RAB22A	ENSPPYP00000005592	ENSPPYP00000012479	APPL2 isoform 1.	RAB22A, member RAS oncogene family.	0.788
APPL2	RAB31	ENSPPYP00000005592	ENSPPYP00000010107	APPL2 isoform 1.	RAB31, member RAS oncogene family.	0.788
APPL2	RBSN	ENSPPYP00000005592	ENSPPYP00000014998	APPL2 isoform 1.	Rabenosyn, RAB effector.	0.457
GAK	RAB22A	ENSPPYP00000016219	ENSPPYP00000012479	GAK isoform 7.	RAB22A, member RAS oncogene family.	0.703
GAK	RAB31	ENSPPYP00000016219	ENSPPYP00000010107	GAK isoform 7.	RAB31, member RAS oncogene family.	0.703
GDI1	RAB22A	ENSPPYP00000023371	ENSPPYP00000012479	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB22A, member RAS oncogene family.	0.863
GDI1	RAB31	ENSPPYP00000023371	ENSPPYP00000010107	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RAB31, member RAS oncogene family.	0.763
GDI1	RABGEF1	ENSPPYP00000023371	ENSPPYP00000019637	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	RABGEF1 isoform 2.	0.913
GDI1	RABGGTA	ENSPPYP00000023371	ENSPPYP00000006478	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	Geranylgeranyl transferase type-2 subunit alpha; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of Rab proteins with the C-terminal sequence -XXCC, -XCXC and -CCXX, such as RAB1A, RAB3A, RAB5A and RAB7A; Belongs to the protein prenyltransferase subunit alpha family.	0.489
RAB22A	APPL1	ENSPPYP00000012479	ENSPPYP00000015409	RAB22A, member RAS oncogene family.	APPL1 isoform 1.	0.788
RAB22A	APPL2	ENSPPYP00000012479	ENSPPYP00000005592	RAB22A, member RAS oncogene family.	APPL2 isoform 1.	0.788
RAB22A	GAK	ENSPPYP00000012479	ENSPPYP00000016219	RAB22A, member RAS oncogene family.	GAK isoform 7.	0.703
RAB22A	GDI1	ENSPPYP00000012479	ENSPPYP00000023371	RAB22A, member RAS oncogene family.	Rab GDP dissociation inhibitor; Regulates the GDP/GTP exchange reaction of most RAB proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP; Belongs to the Rab GDI family.	0.863
RAB22A	RAB31	ENSPPYP00000012479	ENSPPYP00000010107	RAB22A, member RAS oncogene family.	RAB31, member RAS oncogene family.	0.985