| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DNAJA2 | DNAJB1 | ENSPPYP00000008269 | ENSPPYP00000010811 | DnaJ heat shock protein family (Hsp40) member A2. | DnaJ heat shock protein family (Hsp40) member B1. | 0.873 |
| DNAJA2 | DNAJB9 | ENSPPYP00000008269 | ENSPPYP00000020080 | DnaJ heat shock protein family (Hsp40) member A2. | DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similar [...] | 0.669 |
| DNAJA2 | DNAJC5B | ENSPPYP00000008269 | ENSPPYP00000020900 | DnaJ heat shock protein family (Hsp40) member A2. | DNAJC5B isoform 1. | 0.484 |
| DNAJA2 | GAK | ENSPPYP00000008269 | ENSPPYP00000016219 | DnaJ heat shock protein family (Hsp40) member A2. | GAK isoform 7. | 0.434 |
| DNAJA2 | HSPA12A | ENSPPYP00000008269 | ENSPPYP00000003135 | DnaJ heat shock protein family (Hsp40) member A2. | HSPA12A isoform 1. | 0.566 |
| DNAJA2 | HSPA12B | ENSPPYP00000008269 | ENSPPYP00000012078 | DnaJ heat shock protein family (Hsp40) member A2. | HSPA12B isoform 1. | 0.566 |
| DNAJA2 | HSPA13 | ENSPPYP00000008269 | ENSPPYP00000012608 | DnaJ heat shock protein family (Hsp40) member A2. | Heat shock 70 kDa protein 13; Has peptide-independent ATPase activity. | 0.744 |
| DNAJA2 | HSPA4 | ENSPPYP00000008269 | ENSPPYP00000017643 | DnaJ heat shock protein family (Hsp40) member A2. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.756 |
| DNAJA2 | HSPA5 | ENSPPYP00000008269 | ENSPPYP00000021973 | DnaJ heat shock protein family (Hsp40) member A2. | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 0.814 |
| DNAJB1 | DNAJA2 | ENSPPYP00000010811 | ENSPPYP00000008269 | DnaJ heat shock protein family (Hsp40) member B1. | DnaJ heat shock protein family (Hsp40) member A2. | 0.873 |
| DNAJB1 | HIKESHI | ENSPPYP00000010811 | ENSPPYP00000004285 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock protein nuclear import factor hikeshi. | 0.550 |
| DNAJB1 | HSPA12A | ENSPPYP00000010811 | ENSPPYP00000003135 | DnaJ heat shock protein family (Hsp40) member B1. | HSPA12A isoform 1. | 0.552 |
| DNAJB1 | HSPA12B | ENSPPYP00000010811 | ENSPPYP00000012078 | DnaJ heat shock protein family (Hsp40) member B1. | HSPA12B isoform 1. | 0.560 |
| DNAJB1 | HSPA13 | ENSPPYP00000010811 | ENSPPYP00000012608 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock 70 kDa protein 13; Has peptide-independent ATPase activity. | 0.734 |
| DNAJB1 | HSPA4 | ENSPPYP00000010811 | ENSPPYP00000017643 | DnaJ heat shock protein family (Hsp40) member B1. | Heat shock 70 kDa protein 4; Belongs to the heat shock protein 70 family. | 0.989 |
| DNAJB1 | HSPA5 | ENSPPYP00000010811 | ENSPPYP00000021973 | DnaJ heat shock protein family (Hsp40) member B1. | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] | 0.864 |
| DNAJB9 | DNAJA2 | ENSPPYP00000020080 | ENSPPYP00000008269 | DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similar [...] | DnaJ heat shock protein family (Hsp40) member A2. | 0.669 |
| DNAJB9 | HIKESHI | ENSPPYP00000020080 | ENSPPYP00000004285 | DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similar [...] | Heat shock protein nuclear import factor hikeshi. | 0.516 |
| DNAJB9 | HSPA12A | ENSPPYP00000020080 | ENSPPYP00000003135 | DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similar [...] | HSPA12A isoform 1. | 0.480 |
| DNAJB9 | HSPA12B | ENSPPYP00000020080 | ENSPPYP00000012078 | DnaJ homolog subfamily B member 9; Co-chaperone for Hsp70 protein HSPA5/BiP that acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR) (By similarity). J domain-containing co-chaperones stimulate the ATPase activity of Hsp70 proteins and are required for efficient substrate recognition by Hsp70 proteins (By similarity). In the unstressed endoplasmic reticulum, interacts with the luminal region of ERN1/IRE1 and selectively recruits HSPA5/BiP: HSPA5/BiP disrupts the dimerization of the active ERN1/IRE1 luminal region, thereby inactivating ERN1/IRE1 (By similar [...] | HSPA12B isoform 1. | 0.451 |
