| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADAMTS5 | BCAN | ENSPPYP00000012634 | ENSPPYP00000000820 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | BCAN isoform 1. | 0.952 |
| ADAMTS5 | COL10A1 | ENSPPYP00000012634 | ENSPPYP00000018969 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Collagen type X alpha 1 chain. | 0.497 |
| ADAMTS5 | COL2A1 | ENSPPYP00000012634 | ENSPPYP00000005079 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Collagen type II alpha 1 chain. | 0.665 |
| ADAMTS5 | ENSPPYP00000023804 | ENSPPYP00000012634 | ENSPPYP00000023804 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | LOW QUALITY PROTEIN: A disintegrin and metalloproteinase with thrombospondin motifs 7. | 0.571 |
| ADAMTS5 | IL1B | ENSPPYP00000012634 | ENSPPYP00000013573 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.520 |
| ADAMTS5 | MMP13 | ENSPPYP00000012634 | ENSPPYP00000004364 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Matrix metallopeptidase 13. | 0.725 |
| ADAMTS5 | MMP3 | ENSPPYP00000012634 | ENSPPYP00000004363 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Matrix metallopeptidase 3. | 0.632 |
| ADAMTS5 | SDC4 | ENSPPYP00000012634 | ENSPPYP00000012352 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Belongs to the syndecan proteoglycan family. | 0.525 |
| ADAMTS5 | TIMP3 | ENSPPYP00000012634 | ENSPPYP00000013114 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | TIMP metallopeptidase inhibitor 3. | 0.533 |
| ADAMTS5 | VCAN | ENSPPYP00000012634 | ENSPPYP00000017455 | ADAM metallopeptidase with thrombospondin type 1 motif 5. | VCAN isoform 1. | 0.529 |
| BCAN | ADAMTS5 | ENSPPYP00000000820 | ENSPPYP00000012634 | BCAN isoform 1. | ADAM metallopeptidase with thrombospondin type 1 motif 5. | 0.952 |
| BCAN | MMP13 | ENSPPYP00000000820 | ENSPPYP00000004364 | BCAN isoform 1. | Matrix metallopeptidase 13. | 0.570 |
| BCAN | SDC4 | ENSPPYP00000000820 | ENSPPYP00000012352 | BCAN isoform 1. | Syndecan-4; Cell surface proteoglycan that bears heparan sulfate. Regulates exosome biogenesis in concert with SDCBP and PDCD6IP. Belongs to the syndecan proteoglycan family. | 0.570 |
| COL10A1 | ADAMTS5 | ENSPPYP00000018969 | ENSPPYP00000012634 | Collagen type X alpha 1 chain. | ADAM metallopeptidase with thrombospondin type 1 motif 5. | 0.497 |
| COL10A1 | COL2A1 | ENSPPYP00000018969 | ENSPPYP00000005079 | Collagen type X alpha 1 chain. | Collagen type II alpha 1 chain. | 0.659 |
| COL10A1 | MMP13 | ENSPPYP00000018969 | ENSPPYP00000004364 | Collagen type X alpha 1 chain. | Matrix metallopeptidase 13. | 0.744 |
| COL10A1 | MMP3 | ENSPPYP00000018969 | ENSPPYP00000004363 | Collagen type X alpha 1 chain. | Matrix metallopeptidase 3. | 0.431 |
| COL2A1 | ADAMTS5 | ENSPPYP00000005079 | ENSPPYP00000012634 | Collagen type II alpha 1 chain. | ADAM metallopeptidase with thrombospondin type 1 motif 5. | 0.665 |
| COL2A1 | COL10A1 | ENSPPYP00000005079 | ENSPPYP00000018969 | Collagen type II alpha 1 chain. | Collagen type X alpha 1 chain. | 0.659 |
| COL2A1 | IL1B | ENSPPYP00000005079 | ENSPPYP00000013573 | Collagen type II alpha 1 chain. | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. | 0.442 |
