| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADSL | ATIC | ENSPPYP00000013221 | ENSPPYP00000014690 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | 0.999 |
| ADSL | ENSPPYP00000021704 | ENSPPYP00000013221 | ENSPPYP00000021704 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | annotation not available | 0.978 |
| ADSL | GART | ENSPPYP00000013221 | ENSPPYP00000012701 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ADSL | MTHFD1 | ENSPPYP00000013221 | ENSPPYP00000006705 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.485 |
| ADSL | MTHFD1L | ENSPPYP00000013221 | ENSPPYP00000019152 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | MTHFD1L isoform 1. | 0.485 |
| ADSL | MTHFD2L | ENSPPYP00000013221 | ENSPPYP00000016565 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | MTHFD2L isoform 10. | 0.693 |
| ADSL | PAICS | ENSPPYP00000013221 | ENSPPYP00000016477 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily. | 0.997 |
| ADSL | PPAT | ENSPPYP00000013221 | ENSPPYP00000023924 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.977 |
| ADSL | SHMT1 | ENSPPYP00000013221 | ENSPPYP00000009057 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.740 |
| ADSL | SHMT2 | ENSPPYP00000013221 | ENSPPYP00000005336 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.740 |
| ATIC | ADSL | ENSPPYP00000014690 | ENSPPYP00000013221 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.999 |
| ATIC | ENSPPYP00000021704 | ENSPPYP00000014690 | ENSPPYP00000021704 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | annotation not available | 0.919 |
| ATIC | GART | ENSPPYP00000014690 | ENSPPYP00000012701 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.999 |
| ATIC | MTHFD1 | ENSPPYP00000014690 | ENSPPYP00000006705 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | C-1-tetrahydrofolate synthase, cytoplasmic; In the C-terminal section; belongs to the formate-- tetrahydrofolate ligase family. | 0.983 |
| ATIC | MTHFD1L | ENSPPYP00000014690 | ENSPPYP00000019152 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | MTHFD1L isoform 1. | 0.983 |
| ATIC | MTHFD2L | ENSPPYP00000014690 | ENSPPYP00000016565 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | MTHFD2L isoform 10. | 0.961 |
| ATIC | PAICS | ENSPPYP00000014690 | ENSPPYP00000016477 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Phosphoribosylaminoimidazole-succinocarboxamide synthase; In the C-terminal section; belongs to the AIR carboxylase family. Class II subfamily. | 0.935 |
| ATIC | PPAT | ENSPPYP00000014690 | ENSPPYP00000023924 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.982 |
| ATIC | SHMT1 | ENSPPYP00000014690 | ENSPPYP00000009057 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. | 0.978 |
| ATIC | SHMT2 | ENSPPYP00000014690 | ENSPPYP00000005336 | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Bifunctional enzyme that catalyzes 2 steps in purine biosynthesis; Belongs to the PurH family. | Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. | 0.978 |
