| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0039615 | DDX58 | ENSPPYP00000013953 | ENSPPYP00000021455 | EIF2AK2 isoform 5. | DDX58 isoform 2. | 0.958 |
| CR201_G0039615 | HERC5 | ENSPPYP00000013953 | ENSPPYP00000016665 | EIF2AK2 isoform 5. | HERC5 isoform 1. | 0.801 |
| CR201_G0039615 | ISG15 | ENSPPYP00000013953 | ENSPPYP00000002343 | EIF2AK2 isoform 5. | ISG15 ubiquitin like modifier. | 0.979 |
| CR201_G0039615 | MX1 | ENSPPYP00000013953 | ENSPPYP00000012765 | EIF2AK2 isoform 5. | Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity. | 0.861 |
| CR201_G0039615 | MX2 | ENSPPYP00000013953 | ENSPPYP00000012763 | EIF2AK2 isoform 5. | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.849 |
| CR201_G0039615 | OAS2 | ENSPPYP00000013953 | ENSPPYP00000005681 | EIF2AK2 isoform 5. | OAS2 isoform 1. | 0.805 |
| CR201_G0039615 | RSAD2 | ENSPPYP00000013953 | ENSPPYP00000014148 | EIF2AK2 isoform 5. | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.944 |
| CR201_G0039615 | USP41 | ENSPPYP00000013953 | ENSPPYP00000022342 | EIF2AK2 isoform 5. | Ubl carboxyl-terminal hydrolase 18; Involved in the regulation of inflammatory response to interferon type 1. Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. | 0.818 |
| DDX58 | CR201_G0039615 | ENSPPYP00000021455 | ENSPPYP00000013953 | DDX58 isoform 2. | EIF2AK2 isoform 5. | 0.958 |
| DDX58 | HERC5 | ENSPPYP00000021455 | ENSPPYP00000016665 | DDX58 isoform 2. | HERC5 isoform 1. | 0.802 |
| DDX58 | ISG15 | ENSPPYP00000021455 | ENSPPYP00000002343 | DDX58 isoform 2. | ISG15 ubiquitin like modifier. | 0.999 |
| DDX58 | MX1 | ENSPPYP00000021455 | ENSPPYP00000012765 | DDX58 isoform 2. | Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity. | 0.819 |
| DDX58 | MX2 | ENSPPYP00000021455 | ENSPPYP00000012763 | DDX58 isoform 2. | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.857 |
| DDX58 | OAS2 | ENSPPYP00000021455 | ENSPPYP00000005681 | DDX58 isoform 2. | OAS2 isoform 1. | 0.907 |
| DDX58 | RSAD2 | ENSPPYP00000021455 | ENSPPYP00000014148 | DDX58 isoform 2. | Radical S-adenosyl methionine domain-containing protein 2; Interferon-inducible iron-sulfur (4FE-4S) cluster-binding antiviral protein which plays a major role in the cell antiviral state induced by type I and type II interferon. Can inhibit a wide range of viruses, including west Nile virus (WNV), dengue virus, sindbis virus, influenza A virus, sendai virus and vesicular stomatitis virus (VSV). Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts. This is accomplished, at least in part, thro [...] | 0.939 |
| DDX58 | USP41 | ENSPPYP00000021455 | ENSPPYP00000022342 | DDX58 isoform 2. | Ubl carboxyl-terminal hydrolase 18; Involved in the regulation of inflammatory response to interferon type 1. Can efficiently cleave only ISG15 fusions including native ISG15 conjugates linked via isopeptide bonds. Necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms. | 0.930 |
| GAK | ISG15 | ENSPPYP00000016219 | ENSPPYP00000002343 | GAK isoform 7. | ISG15 ubiquitin like modifier. | 0.732 |
| GAK | ITSN2 | ENSPPYP00000016219 | ENSPPYP00000014069 | GAK isoform 7. | ITSN2 isoform 3. | 0.868 |
| GAK | MX1 | ENSPPYP00000016219 | ENSPPYP00000012765 | GAK isoform 7. | Interferon-induced GTP-binding protein Mx1; Interferon-induced dynamin-like GTPase with antiviral activity. | 0.892 |
| GAK | MX2 | ENSPPYP00000016219 | ENSPPYP00000012763 | GAK isoform 7. | MX dynamin like GTPase 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | 0.892 |
