| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BCKDHB | CTH | ENSPPYP00000018803 | ENSPPYP00000024468 | BCKDHB isoform 1. | CTH isoform 3. | 0.823 |
| BCKDHB | PDHB | ENSPPYP00000018803 | ENSPPYP00000015393 | BCKDHB isoform 1. | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle. | 0.511 |
| BCKDHB | TXNRD2 | ENSPPYP00000018803 | ENSPPYP00000012925 | BCKDHB isoform 1. | Thioredoxin reductase 2. | 0.794 |
| BCKDHB | TXNRD3 | ENSPPYP00000018803 | ENSPPYP00000015043 | BCKDHB isoform 1. | TXNRD3 isoform 1. | 0.794 |
| CR201_G0024663 | GLRX2 | ENSPPYP00000013134 | ENSPPYP00000000449 | TXN2 isoform 1. | Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...] | 0.493 |
| CR201_G0024663 | TXNRD2 | ENSPPYP00000013134 | ENSPPYP00000012925 | TXN2 isoform 1. | Thioredoxin reductase 2. | 0.967 |
| CR201_G0024663 | TXNRD3 | ENSPPYP00000013134 | ENSPPYP00000015043 | TXN2 isoform 1. | TXNRD3 isoform 1. | 0.772 |
| CR201_G0027561 | CTH | ENSPPYP00000022040 | ENSPPYP00000024468 | KYAT1 isoform 2. | CTH isoform 3. | 0.945 |
| CR201_G0027561 | KYAT3 | ENSPPYP00000022040 | ENSPPYP00000001362 | KYAT1 isoform 2. | Kynurenine aminotransferase 3. | 0.903 |
| CR201_G0027561 | TXNRD2 | ENSPPYP00000022040 | ENSPPYP00000012925 | KYAT1 isoform 2. | Thioredoxin reductase 2. | 0.916 |
| CR201_G0027561 | TXNRD3 | ENSPPYP00000022040 | ENSPPYP00000015043 | KYAT1 isoform 2. | TXNRD3 isoform 1. | 0.916 |
| CTH | BCKDHB | ENSPPYP00000024468 | ENSPPYP00000018803 | CTH isoform 3. | BCKDHB isoform 1. | 0.823 |
| CTH | CR201_G0027561 | ENSPPYP00000024468 | ENSPPYP00000022040 | CTH isoform 3. | KYAT1 isoform 2. | 0.945 |
| CTH | KYAT3 | ENSPPYP00000024468 | ENSPPYP00000001362 | CTH isoform 3. | Kynurenine aminotransferase 3. | 0.945 |
| CTH | SCLY | ENSPPYP00000024468 | ENSPPYP00000014893 | CTH isoform 3. | SCLY isoform 2. | 0.418 |
| CTH | TXNRD2 | ENSPPYP00000024468 | ENSPPYP00000012925 | CTH isoform 3. | Thioredoxin reductase 2. | 0.915 |
| CTH | TXNRD3 | ENSPPYP00000024468 | ENSPPYP00000015043 | CTH isoform 3. | TXNRD3 isoform 1. | 0.915 |
| GLRX2 | CR201_G0024663 | ENSPPYP00000000449 | ENSPPYP00000013134 | Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...] | TXN2 isoform 1. | 0.493 |
| GLRX2 | TXNRD2 | ENSPPYP00000000449 | ENSPPYP00000012925 | Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...] | Thioredoxin reductase 2. | 0.813 |
| GLRX2 | TXNRD3 | ENSPPYP00000000449 | ENSPPYP00000015043 | Glutaredoxin-2, mitochondrial; Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylat [...] | TXNRD3 isoform 1. | 0.579 |
