| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BOP1 | DDX54 | ENSPPYP00000024742 | ENSPPYP00000005686 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | 0.955 |
| BOP1 | METTL1 | ENSPPYP00000024742 | ENSPPYP00000005363 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | 0.710 |
| BOP1 | RPF2 | ENSPPYP00000024742 | ENSPPYP00000018947 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | Ribosome production factor 2 homolog. | 0.981 |
| BOP1 | TBL3 | ENSPPYP00000024742 | ENSPPYP00000007898 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | TBL3 isoform 1. | 0.936 |
| BOP1 | TRMT2A | ENSPPYP00000024742 | ENSPPYP00000012931 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | TRMT2A isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.782 |
| BOP1 | TRMT61A | ENSPPYP00000024742 | ENSPPYP00000007013 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.821 |
| BOP1 | TRMT61B | ENSPPYP00000024742 | ENSPPYP00000013992 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | TRMT61B isoform 1. | 0.717 |
| DDX54 | BOP1 | ENSPPYP00000005686 | ENSPPYP00000024742 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.955 |
| DDX54 | RPF2 | ENSPPYP00000005686 | ENSPPYP00000018947 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | Ribosome production factor 2 homolog. | 0.890 |
| DDX54 | TBL3 | ENSPPYP00000005686 | ENSPPYP00000007898 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | TBL3 isoform 1. | 0.807 |
| DDX54 | TRMT2A | ENSPPYP00000005686 | ENSPPYP00000012931 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | TRMT2A isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.599 |
| DDX54 | TRMT61A | ENSPPYP00000005686 | ENSPPYP00000007013 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.643 |
| DDX54 | TRMT61B | ENSPPYP00000005686 | ENSPPYP00000013992 | ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. | TRMT61B isoform 1. | 0.509 |
| METTL1 | BOP1 | ENSPPYP00000005363 | ENSPPYP00000024742 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.710 |
| METTL1 | RPF2 | ENSPPYP00000005363 | ENSPPYP00000018947 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | Ribosome production factor 2 homolog. | 0.752 |
| METTL1 | TRMT2A | ENSPPYP00000005363 | ENSPPYP00000012931 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRMT2A isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.609 |
| METTL1 | TRMT61A | ENSPPYP00000005363 | ENSPPYP00000007013 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A; Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. | 0.786 |
| METTL1 | TRMT61B | ENSPPYP00000005363 | ENSPPYP00000013992 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family. | TRMT61B isoform 1. | 0.733 |
| OGFOD2 | TRMT2A | ENSPPYP00000005785 | ENSPPYP00000012931 | 2-oxoglutarate and iron dependent oxygenase domain containing 2. | TRMT2A isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.792 |
| RANBP1 | TRMT2A | ENSPPYP00000012932 | ENSPPYP00000012931 | RANBP1 isoform 6. | TRMT2A isoform 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. | 0.700 |