STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IL2RBIL2RB isoform 1. (462 aa)    
Predicted Functional Partners:
IL2RG
IL2RG isoform 2.
  
 0.999
IL2
Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.
    
 0.998
IL2RA
Interleukin 2 receptor subunit alpha.
   
 0.997
JAK1
Tyrosine-protein kinase.
   
 0.995
IL15
Interleukin; Belongs to the IL-15/IL-21 family.
   
 0.991
IL15RA
IL15RA isoform 5.
    
 0.982
JAK3
Tyrosine-protein kinase.
   
 0.952
ENSPPYP00000011158
annotation not available
   
 0.884
PRF1
PRF1 isoform 2.
   
  
 0.860
ALG13
ALG13 isoform 3.
   
 0.857
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.