Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RAC2Rac family small GTPase 2. (192 aa)    
Predicted Functional Partners:
RAC3
RAC3 isoform 1.
  
 
0.998
RAC1
Rac family small GTPase 1.
  
 
0.998
NCF2
NCF2 isoform 3.
   
 0.992
DOCK1
DOCK1 isoform 1; Belongs to the DOCK family.
   
 0.987
VAV1
VAV1 isoform 2.
   
 0.986
DOCK2
Dedicator of cytokinesis 2; Belongs to the DOCK family.
   
 0.986
PAK1
Non-specific serine/threonine protein kinase.
   
 0.985
PAK2
Non-specific serine/threonine protein kinase.
   
 0.981
NCKAP1
NCK associated protein 1.
   
 0.976
ELMO2
Engulfment and cell motility protein 2; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1 (By similarity).
    
 0.975
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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