Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SOX10SOX10 isoform 2. (436 aa)    
Predicted Functional Partners:
PAX3
PAX3 isoform 1.
   
 0.976
EGR2
Early growth response 2.
    
 0.912
SOX8
SRY-box transcription factor 8.
   
   0.792
MITF
Melanocyte inducing transcription factor.
    
 0.785
NR5A1
NR5A1 isoform 2.
    
 0.772
PAX7
PAX7 isoform 2.
   
 0.747
ZNF143
Zinc finger protein 143.
    
 0.738
SOX9
SRY-box transcription factor 9.
   
 
 0.737
FBXW7
FBXW7 isoform 8.
    
 
 0.717
MBP
MBP isoform 10.
   
 0.714
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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