KIAA0930 protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPPYP00000019656	ENSPPYP00000023003	ENSPPYP00000019656	ENSPPYP00000023003	annotation not available	annotation not available	0.908
ENSPPYP00000019656	KIAA0930	ENSPPYP00000019656	ENSPPYP00000013315	annotation not available	KIAA0930 isoform 1.	0.709
ENSPPYP00000019656	SFN	ENSPPYP00000019656	ENSPPYP00000001937	annotation not available	SFN isoform 1; Belongs to the 14-3-3 family.	0.932
ENSPPYP00000019656	YWHAB	ENSPPYP00000019656	ENSPPYP00000012330	annotation not available	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.972
ENSPPYP00000019656	YWHAG	ENSPPYP00000019656	ENSPPYP00000019583	annotation not available	14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family.	0.972
ENSPPYP00000019656	YWHAQ	ENSPPYP00000019656	ENSPPYP00000014137	annotation not available	14-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity).	0.908
ENSPPYP00000023003	ENSPPYP00000019656	ENSPPYP00000023003	ENSPPYP00000019656	annotation not available	annotation not available	0.908
ENSPPYP00000023003	ENSPPYP00000024179	ENSPPYP00000023003	ENSPPYP00000024179	annotation not available	14-3-3 protein epsilon-like isoform X1.	0.908
ENSPPYP00000023003	KIAA0930	ENSPPYP00000023003	ENSPPYP00000013315	annotation not available	KIAA0930 isoform 1.	0.736
ENSPPYP00000023003	SFN	ENSPPYP00000023003	ENSPPYP00000001937	annotation not available	SFN isoform 1; Belongs to the 14-3-3 family.	0.952
ENSPPYP00000023003	YWHAB	ENSPPYP00000023003	ENSPPYP00000012330	annotation not available	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.976
ENSPPYP00000023003	YWHAE	ENSPPYP00000023003	ENSPPYP00000008753	annotation not available	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	0.908
ENSPPYP00000023003	YWHAG	ENSPPYP00000023003	ENSPPYP00000019583	annotation not available	14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family.	0.975
ENSPPYP00000024179	ENSPPYP00000023003	ENSPPYP00000024179	ENSPPYP00000023003	14-3-3 protein epsilon-like isoform X1.	annotation not available	0.908
ENSPPYP00000024179	KIAA0930	ENSPPYP00000024179	ENSPPYP00000013315	14-3-3 protein epsilon-like isoform X1.	KIAA0930 isoform 1.	0.709
ENSPPYP00000024179	SFN	ENSPPYP00000024179	ENSPPYP00000001937	14-3-3 protein epsilon-like isoform X1.	SFN isoform 1; Belongs to the 14-3-3 family.	0.932
ENSPPYP00000024179	YWHAB	ENSPPYP00000024179	ENSPPYP00000012330	14-3-3 protein epsilon-like isoform X1.	14-3-3 protein beta/alpha, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negative regulator of osteogenesis. Blocks the nuclear translocation of the phosphorylated form (by AKT1) of SRPK2 and antagonizes its stimulatory effect on cyclin D1 expression resulting in blockage of neuronal apoptosis elicited by [...]	0.972
ENSPPYP00000024179	YWHAE	ENSPPYP00000024179	ENSPPYP00000008753	14-3-3 protein epsilon-like isoform X1.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	0.901
ENSPPYP00000024179	YWHAG	ENSPPYP00000024179	ENSPPYP00000019583	14-3-3 protein epsilon-like isoform X1.	14-3-3 protein gamma, N-terminally processed; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner; Belongs to the 14-3-3 family.	0.972
ENSPPYP00000024179	YWHAQ	ENSPPYP00000024179	ENSPPYP00000014137	14-3-3 protein epsilon-like isoform X1.	14-3-3 protein theta; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1 (By similarity).	0.908