STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GTPBP1-2GTP-binding protein 1. (296 aa)    
Predicted Functional Partners:
NPC1
NPC1 isoform 1.
   
  
 0.686
GP2
GP2 isoform 2.
      
 0.679
GP5
GP5 isoform 1.
      
 0.647
GP9
GP9 isoform 1.
      
 0.605
TFRC
Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Positively regulates T and B cell proliferation through iron uptake (By similarity).
      
 0.562
CD36
CD36 isoform 15; Belongs to the CD36 family.
      
 0.552
PCDH7
PCDH7 isoform 2.
      
 0.549
ITGA2B
Integrin subunit alpha 2b; Belongs to the integrin alpha chain family.
      
 0.501
S100A10
S100A10 isoform 1; Belongs to the S-100 family.
      
 0.459
MBTPS1
MBTPS1 isoform 1.
      
 0.456
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.