| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ENSPPYP00000013398 | JUN | ENSPPYP00000013398 | ENSPPYP00000001511 | annotation not available | JUN isoform 1; Belongs to the bZIP family. | 0.892 |
| ENSPPYP00000013398 | MAP2K1 | ENSPPYP00000013398 | ENSPPYP00000007458 | annotation not available | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | 0.925 |
| ENSPPYP00000013398 | MAP2K2 | ENSPPYP00000013398 | ENSPPYP00000011850 | annotation not available | MAP2K2 isoform 6. | 0.909 |
| ENSPPYP00000013398 | MAPK1 | ENSPPYP00000013398 | ENSPPYP00000023664 | annotation not available | Mitogen-activated protein kinase 1 isoform X1. | 0.899 |
| ENSPPYP00000013398 | MAPK3 | ENSPPYP00000013398 | ENSPPYP00000008184 | annotation not available | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.980 |
| ENSPPYP00000013398 | PEA15 | ENSPPYP00000013398 | ENSPPYP00000000745 | annotation not available | Astrocytic phosphoprotein PEA-15; Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A- mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface (By similarity). | 0.918 |
| ENSPPYP00000013398 | RAF1 | ENSPPYP00000013398 | ENSPPYP00000014975 | annotation not available | RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal- regulated kin [...] | 0.883 |
| ENSPPYP00000013398 | RPS6KA1 | ENSPPYP00000013398 | ENSPPYP00000001941 | annotation not available | Ribosomal protein S6 kinase. | 0.881 |
| ENSPPYP00000013398 | RPS6KA2 | ENSPPYP00000013398 | ENSPPYP00000019227 | annotation not available | Ribosomal protein S6 kinase. | 0.897 |
| ENSPPYP00000013398 | RPS6KA3 | ENSPPYP00000013398 | ENSPPYP00000022577 | annotation not available | Ribosomal protein S6 kinase. | 0.875 |
| JUN | ENSPPYP00000013398 | ENSPPYP00000001511 | ENSPPYP00000013398 | JUN isoform 1; Belongs to the bZIP family. | annotation not available | 0.892 |
| JUN | MAP2K1 | ENSPPYP00000001511 | ENSPPYP00000007458 | JUN isoform 1; Belongs to the bZIP family. | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | 0.513 |
| JUN | MAPK1 | ENSPPYP00000001511 | ENSPPYP00000023664 | JUN isoform 1; Belongs to the bZIP family. | Mitogen-activated protein kinase 1 isoform X1. | 0.892 |
| JUN | MAPK3 | ENSPPYP00000001511 | ENSPPYP00000008184 | JUN isoform 1; Belongs to the bZIP family. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.986 |
| JUN | RAF1 | ENSPPYP00000001511 | ENSPPYP00000014975 | JUN isoform 1; Belongs to the bZIP family. | RAF proto-oncogene serine/threonine-protein kinase; Serine/threonine-protein kinase that acts as a regulatory link between the membrane-associated Ras GTPases and the MAPK/ERK cascade, and this critical regulatory link functions as a switch determining cell fate decisions including proliferation, differentiation, apoptosis, survival and oncogenic transformation. RAF1 activation initiates a mitogen-activated protein kinase (MAPK) cascade that comprises a sequential phosphorylation of the dual-specific MAPK kinases (MAP2K1/MEK1 and MAP2K2/MEK2) and the extracellular signal- regulated kin [...] | 0.560 |
| MAP2K1 | ENSPPYP00000013398 | ENSPPYP00000007458 | ENSPPYP00000013398 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | annotation not available | 0.925 |
| MAP2K1 | JUN | ENSPPYP00000007458 | ENSPPYP00000001511 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | JUN isoform 1; Belongs to the bZIP family. | 0.513 |
| MAP2K1 | MAP2K2 | ENSPPYP00000007458 | ENSPPYP00000011850 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | MAP2K2 isoform 6. | 0.999 |
| MAP2K1 | MAPK1 | ENSPPYP00000007458 | ENSPPYP00000023664 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase 1 isoform X1. | 0.925 |
| MAP2K1 | MAPK3 | ENSPPYP00000007458 | ENSPPYP00000008184 | MAP2K1 isoform 1; Belongs to the protein kinase superfamily. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.999 |
