| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BET1 | LMAN2L | ENSPPYP00000024128 | ENSPPYP00000013465 | BET1 isoform 1. | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | 0.624 |
| BET1 | MCFD2 | ENSPPYP00000024128 | ENSPPYP00000013885 | BET1 isoform 1. | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | 0.407 |
| BET1 | SEC22A | ENSPPYP00000024128 | ENSPPYP00000015071 | BET1 isoform 1. | SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.934 |
| BET1 | SEC22C | ENSPPYP00000024128 | ENSPPYP00000023774 | BET1 isoform 1. | SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.916 |
| BET1 | SEC23A | ENSPPYP00000024128 | ENSPPYP00000006547 | BET1 isoform 1. | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.813 |
| BET1 | SEC24C | ENSPPYP00000024128 | ENSPPYP00000002707 | BET1 isoform 1. | SEC24C isoform 1. | 0.784 |
| BET1 | TMED10 | ENSPPYP00000024128 | ENSPPYP00000024352 | BET1 isoform 1. | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | 0.712 |
| BET1 | TMED2 | ENSPPYP00000024128 | ENSPPYP00000024232 | BET1 isoform 1. | Transmembrane p24 trafficking protein 2. | 0.708 |
| LMAN2L | BET1 | ENSPPYP00000013465 | ENSPPYP00000024128 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | BET1 isoform 1. | 0.624 |
| LMAN2L | MCFD2 | ENSPPYP00000013465 | ENSPPYP00000013885 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | 0.682 |
| LMAN2L | RNF135 | ENSPPYP00000013465 | ENSPPYP00000009157 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Ring finger protein 135. | 0.649 |
| LMAN2L | SEC22A | ENSPPYP00000013465 | ENSPPYP00000015071 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | SEC22 homolog A, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.608 |
| LMAN2L | SEC22C | ENSPPYP00000013465 | ENSPPYP00000023774 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | SEC22 homolog C, vesicle trafficking protein; Belongs to the synaptobrevin family. | 0.608 |
| LMAN2L | SEC23A | ENSPPYP00000013465 | ENSPPYP00000006547 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex. Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.603 |
| LMAN2L | SEC24C | ENSPPYP00000013465 | ENSPPYP00000002707 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | SEC24C isoform 1. | 0.607 |
| LMAN2L | TMED10 | ENSPPYP00000013465 | ENSPPYP00000024352 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | 0.756 |
| LMAN2L | TMED2 | ENSPPYP00000013465 | ENSPPYP00000024232 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Transmembrane p24 trafficking protein 2. | 0.754 |
| LMAN2L | TMEM161B | ENSPPYP00000013465 | ENSPPYP00000017464 | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | Transmembrane protein 161B. | 0.622 |
| MCFD2 | BET1 | ENSPPYP00000013885 | ENSPPYP00000024128 | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | BET1 isoform 1. | 0.407 |
| MCFD2 | LMAN2L | ENSPPYP00000013885 | ENSPPYP00000013465 | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | 0.682 |
