STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZAP70Tyrosine-protein kinase. (559 aa)    
Predicted Functional Partners:
CD247
CD247 isoform 2.
   
 0.999
LCK
Tyrosine-protein kinase.
   
0.994
LCP2
LCP2 isoform 3.
   
 0.990
CD3E
CD3E isoform 2.
   
 0.986
CBL
Cbl proto-oncogene.
    
 0.986
LAT
LAT isoform 2.
   
 0.978
CD3D
CD3D isoform 1.
   
 0.973
CBLB
Cbl proto-oncogene B.
    
 0.942
VAV1
VAV1 isoform 2.
   
 0.927
GRB2
Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family.
   
0.921
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
Server load: medium (66%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.