IL1R1 protein (Pongo abelii) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IL1A	IL1B	ENSPPYP00000013572	ENSPPYP00000013573	Interleukin-1; Belongs to the IL-1 family.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.999
IL1A	IL1F10	ENSPPYP00000013572	ENSPPYP00000013579	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.529
IL1A	IL1R1	ENSPPYP00000013572	ENSPPYP00000013505	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.966
IL1A	IL1RN	ENSPPYP00000013572	ENSPPYP00000013580	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1.	0.666
IL1A	IRAK1	ENSPPYP00000013572	ENSPPYP00000023353	Interleukin-1; Belongs to the IL-1 family.	Interleukin 1 receptor associated kinase 1.	0.758
IL1A	IRAK2	ENSPPYP00000013572	ENSPPYP00000015274	Interleukin-1; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.	0.604
IL1A	IRAK4	ENSPPYP00000013572	ENSPPYP00000005053	Interleukin-1; Belongs to the IL-1 family.	IRAK4 isoform 6.	0.683
IL1A	MYD88	ENSPPYP00000013572	ENSPPYP00000015673	Interleukin-1; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.766
IL1A	TOLLIP	ENSPPYP00000013572	ENSPPYP00000003370	Interleukin-1; Belongs to the IL-1 family.	Toll interacting protein.	0.479
IL1A	TRAF6	ENSPPYP00000013572	ENSPPYP00000003845	Interleukin-1; Belongs to the IL-1 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.744
IL1B	IL1A	ENSPPYP00000013573	ENSPPYP00000013572	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1; Belongs to the IL-1 family.	0.999
IL1B	IL1F10	ENSPPYP00000013573	ENSPPYP00000013579	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.514
IL1B	IL1R1	ENSPPYP00000013573	ENSPPYP00000013505	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor type 1.	0.970
IL1B	IL1RN	ENSPPYP00000013573	ENSPPYP00000013580	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1.	0.665
IL1B	IRAK1	ENSPPYP00000013573	ENSPPYP00000023353	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin 1 receptor associated kinase 1.	0.784
IL1B	IRAK2	ENSPPYP00000013573	ENSPPYP00000015274	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Interleukin-1 receptor-associated kinase-like 2; Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.	0.597
IL1B	IRAK4	ENSPPYP00000013573	ENSPPYP00000005053	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	IRAK4 isoform 6.	0.717
IL1B	MYD88	ENSPPYP00000013573	ENSPPYP00000015673	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.828
IL1B	TOLLIP	ENSPPYP00000013573	ENSPPYP00000003370	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	Toll interacting protein.	0.707
IL1B	TRAF6	ENSPPYP00000013573	ENSPPYP00000003845	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.770