FHL2 protein (Pongo abelii) - STRING interaction network

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[Homology]

Score

FHL2

FHL2 isoform 4. (459 aa)

Predicted Functional Partners:

FHL3

0.951

TRAF6

0.918

TRAF2

0.917

FHL1

0.914

EGFR

0.823

CNOT1

0.765

FKBP9

0.747

BRCA1

0.745

CNOT2

0.740

ZNF131

0.714

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRCA1	EGFR	ENSPPYP00000009402	ENSPPYP00000019671	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	Receptor protein-tyrosine kinase.	0.487
BRCA1	FHL2	ENSPPYP00000009402	ENSPPYP00000013522	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	FHL2 isoform 4.	0.745
CNOT1	CNOT2	ENSPPYP00000008374	ENSPPYP00000005430	CCR4-NOT transcription complex subunit 1.	CNOT2 isoform 22.	0.998
CNOT1	FHL2	ENSPPYP00000008374	ENSPPYP00000013522	CCR4-NOT transcription complex subunit 1.	FHL2 isoform 4.	0.765
CNOT2	CNOT1	ENSPPYP00000005430	ENSPPYP00000008374	CNOT2 isoform 22.	CCR4-NOT transcription complex subunit 1.	0.998
CNOT2	FHL2	ENSPPYP00000005430	ENSPPYP00000013522	CNOT2 isoform 22.	FHL2 isoform 4.	0.740
EGFR	BRCA1	ENSPPYP00000019671	ENSPPYP00000009402	Receptor protein-tyrosine kinase.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.487
EGFR	FHL2	ENSPPYP00000019671	ENSPPYP00000013522	Receptor protein-tyrosine kinase.	FHL2 isoform 4.	0.823
EGFR	TRAF2	ENSPPYP00000019671	ENSPPYP00000022191	Receptor protein-tyrosine kinase.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.938
EGFR	TRAF6	ENSPPYP00000019671	ENSPPYP00000003845	Receptor protein-tyrosine kinase.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.791
FHL1	FHL2	ENSPPYP00000023242	ENSPPYP00000013522	FHL1 isoform 22.	FHL2 isoform 4.	0.914
FHL1	FHL3	ENSPPYP00000023242	ENSPPYP00000001754	FHL1 isoform 22.	Four and a half LIM domains 3.	0.907
FHL2	BRCA1	ENSPPYP00000013522	ENSPPYP00000009402	FHL2 isoform 4.	Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...]	0.745
FHL2	CNOT1	ENSPPYP00000013522	ENSPPYP00000008374	FHL2 isoform 4.	CCR4-NOT transcription complex subunit 1.	0.765
FHL2	CNOT2	ENSPPYP00000013522	ENSPPYP00000005430	FHL2 isoform 4.	CNOT2 isoform 22.	0.740
FHL2	EGFR	ENSPPYP00000013522	ENSPPYP00000019671	FHL2 isoform 4.	Receptor protein-tyrosine kinase.	0.823
FHL2	FHL1	ENSPPYP00000013522	ENSPPYP00000023242	FHL2 isoform 4.	FHL1 isoform 22.	0.914
FHL2	FHL3	ENSPPYP00000013522	ENSPPYP00000001754	FHL2 isoform 4.	Four and a half LIM domains 3.	0.951
FHL2	FKBP9	ENSPPYP00000013522	ENSPPYP00000019788	FHL2 isoform 4.	Peptidylprolyl isomerase.	0.747
FHL2	TRAF2	ENSPPYP00000013522	ENSPPYP00000022191	FHL2 isoform 4.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.917