Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GCC2GCC2 isoform 3. (1686 aa)    
Predicted Functional Partners:
RAB9B
Ras-related protein Rab-9B; Involved in the transport of proteins between the endosomes and the trans Golgi network.
    
 0.956
RAB6A
Ras-related protein Rab-6A; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Involved in COPI-independent retrograde transport from the Golgi to the ER (By similarity); Belongs to the small GTPase superfamily. Rab family.
    
 0.949
STX10
STX10 isoform 6; Belongs to the syntaxin family.
     
 0.941
ENSPPYP00000008747
annotation not available
   
 0.897
ARL1
ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family.
   
 0.833
THSD1
Thrombospondin type-1 domain-containing protein 1.
      
 0.808
GCC1
GCC1 isoform 3.
     
 0.800
CLASP1
CLASP1 isoform 3.
   
 
 0.787
CKAP2
Cytoskeleton-associated protein 2; Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53- dependent manner (By similarity).
    
 0.779
ACBD7
Acyl-CoA binding domain containing 7.
    
 
 0.751
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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