| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKT1 | BRAF | ENSPPYP00000007036 | ENSPPYP00000020265 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | BRAF isoform 1. | 0.821 |
| AKT1 | LOC100438930 | ENSPPYP00000007036 | ENSPPYP00000013594 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | MDK isoform 6. | 0.662 |
| AKT1 | PIK3CA | ENSPPYP00000007036 | ENSPPYP00000023529 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.996 |
| AKT1 | PIK3R1 | ENSPPYP00000007036 | ENSPPYP00000017341 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.992 |
| AKT1 | STAT3 | ENSPPYP00000007036 | ENSPPYP00000009437 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | Signal transducer and activator of transcription. | 0.774 |
| ALK | LOC100438930 | ENSPPYP00000013987 | ENSPPYP00000013594 | Tyrosine-protein kinase receptor. | MDK isoform 6. | 0.903 |
| ALK | PIK3CA | ENSPPYP00000013987 | ENSPPYP00000023529 | Tyrosine-protein kinase receptor. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.968 |
| ALK | PIK3R1 | ENSPPYP00000013987 | ENSPPYP00000017341 | Tyrosine-protein kinase receptor. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.965 |
| ALK | PTPRZ1 | ENSPPYP00000013987 | ENSPPYP00000020130 | Tyrosine-protein kinase receptor. | PTPRZ1 isoform 1. | 0.542 |
| ALK | STAT3 | ENSPPYP00000013987 | ENSPPYP00000009437 | Tyrosine-protein kinase receptor. | Signal transducer and activator of transcription. | 0.723 |
| BRAF | AKT1 | ENSPPYP00000020265 | ENSPPYP00000007036 | BRAF isoform 1. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.821 |
| BRAF | LOC100438930 | ENSPPYP00000020265 | ENSPPYP00000013594 | BRAF isoform 1. | MDK isoform 6. | 0.668 |
| BRAF | PIK3CA | ENSPPYP00000020265 | ENSPPYP00000023529 | BRAF isoform 1. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.688 |
| BRAF | PIK3R1 | ENSPPYP00000020265 | ENSPPYP00000017341 | BRAF isoform 1. | Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] | 0.520 |
| BRAF | STAT3 | ENSPPYP00000020265 | ENSPPYP00000009437 | BRAF isoform 1. | Signal transducer and activator of transcription. | 0.483 |
| LOC100438930 | AKT1 | ENSPPYP00000013594 | ENSPPYP00000007036 | MDK isoform 6. | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. | 0.662 |
| LOC100438930 | ALK | ENSPPYP00000013594 | ENSPPYP00000013987 | MDK isoform 6. | Tyrosine-protein kinase receptor. | 0.903 |
| LOC100438930 | BRAF | ENSPPYP00000013594 | ENSPPYP00000020265 | MDK isoform 6. | BRAF isoform 1. | 0.668 |
| LOC100438930 | LTK | ENSPPYP00000013594 | ENSPPYP00000007222 | MDK isoform 6. | Tyrosine-protein kinase receptor. | 0.825 |
| LOC100438930 | PIK3CA | ENSPPYP00000013594 | ENSPPYP00000023529 | MDK isoform 6. | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. | 0.679 |
