NAGK protein (Pongo abelii) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

NAGK

N-acetylglucosamine kinase. (390 aa)

Predicted Functional Partners:

GNPNAT1

0.957

PGM3

0.947

RENBP

0.927

HEXA

0.911

HEXB

0.908

CHIA

0.900

ENSPPYP00000001206

0.900

ENSPPYP00000007926

0.900

CNDP2

0.874

OPLAH

0.860

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHIA	ENSPPYP00000001206	ENSPPYP00000001205	ENSPPYP00000001206	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	0.901
CHIA	HEXA	ENSPPYP00000001205	ENSPPYP00000007503	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	0.929
CHIA	HEXB	ENSPPYP00000001205	ENSPPYP00000024213	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	Beta-hexosaminidase.	0.929
CHIA	NAGK	ENSPPYP00000001205	ENSPPYP00000013732	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	N-acetylglucosamine kinase.	0.900
CHIA	RENBP	ENSPPYP00000001205	ENSPPYP00000023350	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	RENBP isoform 1.	0.900
CNDP2	NAGK	ENSPPYP00000010372	ENSPPYP00000013732	Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis.	N-acetylglucosamine kinase.	0.874
CNDP2	OPLAH	ENSPPYP00000010372	ENSPPYP00000021263	Cytosolic non-specific dipeptidase; Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly. Catalyzes the production of N- lactoyl-amino acids from lactate and amino acids by reverse proteolysis.	OPLAH isoform 1.	0.917
ENSPPYP00000001206	CHIA	ENSPPYP00000001206	ENSPPYP00000001205	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	0.901
ENSPPYP00000001206	HEXA	ENSPPYP00000001206	ENSPPYP00000007503	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	0.929
ENSPPYP00000001206	HEXB	ENSPPYP00000001206	ENSPPYP00000024213	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	Beta-hexosaminidase.	0.929
ENSPPYP00000001206	NAGK	ENSPPYP00000001206	ENSPPYP00000013732	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	N-acetylglucosamine kinase.	0.900
ENSPPYP00000001206	RENBP	ENSPPYP00000001206	ENSPPYP00000023350	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	RENBP isoform 1.	0.900
ENSPPYP00000007926	HEXA	ENSPPYP00000007926	ENSPPYP00000007503	annotation not available	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	0.444
ENSPPYP00000007926	HEXB	ENSPPYP00000007926	ENSPPYP00000024213	annotation not available	Beta-hexosaminidase.	0.532
ENSPPYP00000007926	NAGK	ENSPPYP00000007926	ENSPPYP00000013732	annotation not available	N-acetylglucosamine kinase.	0.900
ENSPPYP00000007926	PGM3	ENSPPYP00000007926	ENSPPYP00000018812	annotation not available	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.739
GNPNAT1	NAGK	ENSPPYP00000006615	ENSPPYP00000013732	Glucosamine 6-phosphate N-acetyltransferase.	N-acetylglucosamine kinase.	0.957
GNPNAT1	PGM3	ENSPPYP00000006615	ENSPPYP00000018812	Glucosamine 6-phosphate N-acetyltransferase.	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family.	0.994
HEXA	CHIA	ENSPPYP00000007503	ENSPPYP00000001205	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	Chitinase acidic; Belongs to the glycosyl hydrolase 18 family.	0.929
HEXA	ENSPPYP00000001206	ENSPPYP00000007503	ENSPPYP00000001206	Beta-hexosaminidase subunit alpha; Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues.	LOW QUALITY PROTEIN: acidic mammalian chitinase-like.	0.929