STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIX3SIX3 isoform 1. (210 aa)    
Predicted Functional Partners:
DNMBP
DNMBP isoform 3.
   
  
 0.853
MACC1
Metastasis-associated in colon cancer protein 1; Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling.
      
 0.841
RRS1
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
      
 0.811
MDC1
MDC1 isoform 1.
      
 0.714
ZIC2
ZIC2 isoform 1.
   
  
 0.695
CNTN2
CNTN2 isoform 10.
      
 0.691
DISP1
Dispatched RND transporter family member 1.
      
 0.685
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.683
VSX2
Visual system homeobox 2.
   
  
 0.661
PAX6
PAX6 isoform 13.
   
 
 0.654
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.