| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| EGFR | FGFR1 | ENSPPYP00000019671 | ENSPPYP00000020767 | Receptor protein-tyrosine kinase. | Fibroblast growth factor receptor. | 0.412 |
| EGFR | GRB2 | ENSPPYP00000019671 | ENSPPYP00000009686 | Receptor protein-tyrosine kinase. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.999 |
| EGFR | HRAS | ENSPPYP00000019671 | ENSPPYP00000003333 | Receptor protein-tyrosine kinase. | HRas proto-oncogene, GTPase. | 0.978 |
| EGFR | KRAS | ENSPPYP00000019671 | ENSPPYP00000004987 | Receptor protein-tyrosine kinase. | KRAS proto-oncogene, GTPase. | 0.992 |
| EGFR | NRAS | ENSPPYP00000019671 | ENSPPYP00000001163 | Receptor protein-tyrosine kinase. | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.980 |
| EGFR | PTK2 | ENSPPYP00000019671 | ENSPPYP00000021213 | Receptor protein-tyrosine kinase. | PTK2 isoform 11; Belongs to the protein kinase superfamily. Tyr protein kinase family. | 0.994 |
| EGFR | PTPN11 | ENSPPYP00000019671 | ENSPPYP00000005677 | Receptor protein-tyrosine kinase. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.997 |
| EGFR | SHC1 | ENSPPYP00000019671 | ENSPPYP00000000893 | Receptor protein-tyrosine kinase. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.996 |
| EGFR | SHC3 | ENSPPYP00000019671 | ENSPPYP00000021691 | Receptor protein-tyrosine kinase. | SHC3 isoform 1. | 0.991 |
| EGFR | SOS1 | ENSPPYP00000019671 | ENSPPYP00000013933 | Receptor protein-tyrosine kinase. | SOS1 isoform 2. | 0.996 |
| FGFR1 | EGFR | ENSPPYP00000020767 | ENSPPYP00000019671 | Fibroblast growth factor receptor. | Receptor protein-tyrosine kinase. | 0.412 |
| FGFR1 | GRB2 | ENSPPYP00000020767 | ENSPPYP00000009686 | Fibroblast growth factor receptor. | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | 0.979 |
| FGFR1 | HRAS | ENSPPYP00000020767 | ENSPPYP00000003333 | Fibroblast growth factor receptor. | HRas proto-oncogene, GTPase. | 0.952 |
| FGFR1 | KRAS | ENSPPYP00000020767 | ENSPPYP00000004987 | Fibroblast growth factor receptor. | KRAS proto-oncogene, GTPase. | 0.963 |
| FGFR1 | NRAS | ENSPPYP00000020767 | ENSPPYP00000001163 | Fibroblast growth factor receptor. | GTPase NRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity; Belongs to the small GTPase superfamily. Ras family. | 0.957 |
| FGFR1 | PTPN11 | ENSPPYP00000020767 | ENSPPYP00000005677 | Fibroblast growth factor receptor. | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. | 0.703 |
| FGFR1 | SHC1 | ENSPPYP00000020767 | ENSPPYP00000000893 | Fibroblast growth factor receptor. | SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Participates in signaling downstream of the angiopoietin receptor TEK/TIE2, and plays a role in the regulation of endothelial cell migration and sprouting angiogenesis (By similarity). | 0.949 |
| FGFR1 | SHC3 | ENSPPYP00000020767 | ENSPPYP00000021691 | Fibroblast growth factor receptor. | SHC3 isoform 1. | 0.949 |
| FGFR1 | SOS1 | ENSPPYP00000020767 | ENSPPYP00000013933 | Fibroblast growth factor receptor. | SOS1 isoform 2. | 0.978 |
| GRB2 | EGFR | ENSPPYP00000009686 | ENSPPYP00000019671 | Growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Belongs to the GRB2/sem-5/DRK family. | Receptor protein-tyrosine kinase. | 0.999 |
