| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CR201_G0042741 | PLAAT3 | ENSPPYP00000018451 | ENSPPYP00000004679 | LYPLA2 isoform 1. | Phospholipase A and acyltransferase 3; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (By similarity). For most substrates, PLA1 activity is much higher than PLA2 activity (By similarity). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing th [...] | 0.908 |
| CR201_G0042741 | PLB1 | ENSPPYP00000018451 | ENSPPYP00000013995 | LYPLA2 isoform 1. | PLB1 isoform 2. | 0.910 |
| CR201_G0042741 | PNPLA6 | ENSPPYP00000018451 | ENSPPYP00000010625 | LYPLA2 isoform 1. | Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity). | 0.906 |
| LCAT | LYPLA1 | ENSPPYP00000008444 | ENSPPYP00000020848 | Phosphatidylcholine-sterol acyltransferase. | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.907 |
| LCAT | PLA2G15 | ENSPPYP00000008444 | ENSPPYP00000008453 | Phosphatidylcholine-sterol acyltransferase. | PLA2G15 isoform 3. | 0.900 |
| LCAT | PLAAT3 | ENSPPYP00000008444 | ENSPPYP00000004679 | Phosphatidylcholine-sterol acyltransferase. | Phospholipase A and acyltransferase 3; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (By similarity). For most substrates, PLA1 activity is much higher than PLA2 activity (By similarity). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing th [...] | 0.905 |
| LCAT | PLB1 | ENSPPYP00000008444 | ENSPPYP00000013995 | Phosphatidylcholine-sterol acyltransferase. | PLB1 isoform 2. | 0.931 |
| LCAT | PNPLA6 | ENSPPYP00000008444 | ENSPPYP00000010625 | Phosphatidylcholine-sterol acyltransferase. | Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity). | 0.918 |
| LPCAT1 | LPCAT3 | ENSPPYP00000017114 | ENSPPYP00000004805 | Lysophosphatidylcholine acyltransferase 1. | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | 0.944 |
| LPCAT1 | LPCAT4 | ENSPPYP00000017114 | ENSPPYP00000007155 | Lysophosphatidylcholine acyltransferase 1. | LPCAT4 isoform 1. | 0.939 |
| LPCAT1 | LYPLA1 | ENSPPYP00000017114 | ENSPPYP00000020848 | Lysophosphatidylcholine acyltransferase 1. | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.912 |
| LPCAT1 | PLA2G15 | ENSPPYP00000017114 | ENSPPYP00000008453 | Lysophosphatidylcholine acyltransferase 1. | PLA2G15 isoform 3. | 0.907 |
| LPCAT1 | PLAAT3 | ENSPPYP00000017114 | ENSPPYP00000004679 | Lysophosphatidylcholine acyltransferase 1. | Phospholipase A and acyltransferase 3; Exhibits both phospholipase A1/2 and acyltransferase activities (By similarity). Shows phospholipase A1 (PLA1) and A2 (PLA2), catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (By similarity). For most substrates, PLA1 activity is much higher than PLA2 activity (By similarity). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (By similarity). Shows N-acyltransferase activity, catalyzing th [...] | 0.913 |
| LPCAT1 | PLB1 | ENSPPYP00000017114 | ENSPPYP00000013995 | Lysophosphatidylcholine acyltransferase 1. | PLB1 isoform 2. | 0.911 |
| LPCAT1 | PNPLA6 | ENSPPYP00000017114 | ENSPPYP00000010625 | Lysophosphatidylcholine acyltransferase 1. | Neuropathy target esterase; Phospholipase B that deacylates intracellular phosphatidylcholine (PtdCho), generating glycerophosphocholine (GroPtdCho). This deacylation occurs at both sn-2 and sn-1 positions of PtdCho. Its specific chemical modification by certain organophosphorus (OP) compounds leads to distal axonopathy (By similarity). | 0.903 |
| LPCAT3 | LPCAT1 | ENSPPYP00000004805 | ENSPPYP00000017114 | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | Lysophosphatidylcholine acyltransferase 1. | 0.944 |
| LPCAT3 | LPCAT4 | ENSPPYP00000004805 | ENSPPYP00000007155 | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | LPCAT4 isoform 1. | 0.942 |
| LPCAT3 | LYPLA1 | ENSPPYP00000004805 | ENSPPYP00000020848 | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.910 |
| LPCAT3 | MBOAT1 | ENSPPYP00000004805 | ENSPPYP00000018192 | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. | 0.902 |
| LPCAT3 | PLA2G15 | ENSPPYP00000004805 | ENSPPYP00000008453 | LPCAT3 isoform 2; Belongs to the membrane-bound acyltransferase family. | PLA2G15 isoform 3. | 0.905 |
