| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ASPSCR1 | NSFL1C | ENSPPYP00000009833 | ENSPPYP00000012121 | ASPSCR1 isoform 2. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.943 |
| ASPSCR1 | UBXN1 | ENSPPYP00000009833 | ENSPPYP00000003643 | ASPSCR1 isoform 2. | UBXN1 isoform 1. | 0.545 |
| ASPSCR1 | UBXN10 | ENSPPYP00000009833 | ENSPPYP00000002058 | ASPSCR1 isoform 2. | UBXN10 isoform 1. | 0.928 |
| ASPSCR1 | UBXN2A | ENSPPYP00000009833 | ENSPPYP00000014077 | ASPSCR1 isoform 2. | UBXN2A isoform 2. | 0.953 |
| ASPSCR1 | UBXN4 | ENSPPYP00000009833 | ENSPPYP00000014304 | ASPSCR1 isoform 2. | UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. | 0.637 |
| ASPSCR1 | UBXN6 | ENSPPYP00000009833 | ENSPPYP00000010548 | ASPSCR1 isoform 2. | UBXN6 isoform 3. | 0.942 |
| ASPSCR1 | UBXN8 | ENSPPYP00000009833 | ENSPPYP00000020726 | ASPSCR1 isoform 2. | UBXN8 isoform 1. | 0.472 |
| ASPSCR1 | VCP | ENSPPYP00000009833 | ENSPPYP00000021408 | ASPSCR1 isoform 2. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.932 |
| NSFL1C | ASPSCR1 | ENSPPYP00000012121 | ENSPPYP00000009833 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | ASPSCR1 isoform 2. | 0.943 |
| NSFL1C | SVIP | ENSPPYP00000012121 | ENSPPYP00000003920 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Small VCP/p97-interacting protein; Belongs to the SVIP family. | 0.915 |
| NSFL1C | UBXN1 | ENSPPYP00000012121 | ENSPPYP00000003643 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBXN1 isoform 1. | 0.961 |
| NSFL1C | UBXN10 | ENSPPYP00000012121 | ENSPPYP00000002058 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBXN10 isoform 1. | 0.939 |
| NSFL1C | UBXN2A | ENSPPYP00000012121 | ENSPPYP00000014077 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBXN2A isoform 2. | 0.991 |
| NSFL1C | UBXN4 | ENSPPYP00000012121 | ENSPPYP00000014304 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBX domain-containing protein 4; Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD. | 0.937 |
| NSFL1C | UBXN6 | ENSPPYP00000012121 | ENSPPYP00000010548 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBXN6 isoform 3. | 0.994 |
| NSFL1C | UBXN8 | ENSPPYP00000012121 | ENSPPYP00000020726 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | UBXN8 isoform 1. | 0.946 |
| NSFL1C | VCP | ENSPPYP00000012121 | ENSPPYP00000021408 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | Transitional endoplasmic reticulum ATPase isoform X1. | 0.999 |
| NSFL1C | VCPIP1 | ENSPPYP00000012121 | ENSPPYP00000020915 | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | VCPIP1 isoform 1. | 0.966 |
| SVIP | NSFL1C | ENSPPYP00000003920 | ENSPPYP00000012121 | Small VCP/p97-interacting protein; Belongs to the SVIP family. | NSFL1 cofactor p47; Reduces the ATPase activity of VCP. Necessary for the fragmentation of Golgi stacks during mitosis and for VCP-mediated reassembly of Golgi stacks after mitosis. May play a role in VCP- mediated formation of transitional endoplasmic reticulum (tER). Inhibits the activity of CTSL (in vitro). Together with UBXN2B/p37, regulates the centrosomal levels of kinase AURKA/Aurora A levels during mitotic progression by promoting AURKA removal from centrosomes in prophase. Also, regulates spindle orientation during mitosis. Belongs to the NSFL1C family. | 0.915 |
| SVIP | UBXN1 | ENSPPYP00000003920 | ENSPPYP00000003643 | Small VCP/p97-interacting protein; Belongs to the SVIP family. | UBXN1 isoform 1. | 0.914 |
