| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AOC1 | HDC | ENSPPYP00000020382 | ENSPPYP00000007330 | Amine oxidase. | HDC isoform 2. | 0.946 |
| AOC1 | HNMT | ENSPPYP00000020382 | ENSPPYP00000014313 | Amine oxidase. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.968 |
| AOC1 | MAOA | ENSPPYP00000020382 | ENSPPYP00000022677 | Amine oxidase. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.932 |
| AOC1 | MAOB | ENSPPYP00000020382 | ENSPPYP00000022680 | Amine oxidase. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.937 |
| CDHR3 | HNMT | ENSPPYP00000020487 | ENSPPYP00000014313 | CDHR3 isoform 2. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.491 |
| CDHR3 | TRAF3IP1 | ENSPPYP00000020487 | ENSPPYP00000014902 | CDHR3 isoform 2. | TRAF3IP1 isoform 2. | 0.521 |
| CR201_G0034515 | H3-4 | ENSPPYP00000008244 | ENSPPYP00000000136 | SETD1A isoform 1. | Histone H3; Belongs to the histone H3 family. | 0.786 |
| CR201_G0034515 | HNMT | ENSPPYP00000008244 | ENSPPYP00000014313 | SETD1A isoform 1. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.525 |
| H3-4 | CR201_G0034515 | ENSPPYP00000000136 | ENSPPYP00000008244 | Histone H3; Belongs to the histone H3 family. | SETD1A isoform 1. | 0.786 |
| H3-4 | HDAC9 | ENSPPYP00000000136 | ENSPPYP00000019901 | Histone H3; Belongs to the histone H3 family. | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | 0.617 |
| H3-4 | HNMT | ENSPPYP00000000136 | ENSPPYP00000014313 | Histone H3; Belongs to the histone H3 family. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.491 |
| H3-4 | MAOA | ENSPPYP00000000136 | ENSPPYP00000022677 | Histone H3; Belongs to the histone H3 family. | Amine oxidase [flavin-containing] A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (By similarity). | 0.414 |
| H3-4 | MAOB | ENSPPYP00000000136 | ENSPPYP00000022680 | Histone H3; Belongs to the histone H3 family. | Amine oxidase [flavin-containing] B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (By similarity). | 0.406 |
| HDAC9 | H3-4 | ENSPPYP00000019901 | ENSPPYP00000000136 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Histone H3; Belongs to the histone H3 family. | 0.617 |
| HDAC9 | HNMT | ENSPPYP00000019901 | ENSPPYP00000014313 | Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.512 |
| HDC | AOC1 | ENSPPYP00000007330 | ENSPPYP00000020382 | HDC isoform 2. | Amine oxidase. | 0.946 |
| HDC | HNMT | ENSPPYP00000007330 | ENSPPYP00000014313 | HDC isoform 2. | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | 0.954 |
| HNMT | AOC1 | ENSPPYP00000014313 | ENSPPYP00000020382 | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | Amine oxidase. | 0.968 |
| HNMT | CDHR3 | ENSPPYP00000014313 | ENSPPYP00000020487 | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | CDHR3 isoform 2. | 0.491 |
| HNMT | CR201_G0034515 | ENSPPYP00000014313 | ENSPPYP00000008244 | Histamine N-methyltransferase; Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine; Belongs to the class I-like SAM-binding methyltransferase superfamily. HNMT family. | SETD1A isoform 1. | 0.525 |
