| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADPGK | G6PC2 | ENSPPYP00000007509 | ENSPPYP00000014406 | ADPGK isoform 4. | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | 0.905 |
| ADPGK | GALM | ENSPPYP00000007509 | ENSPPYP00000013940 | ADPGK isoform 4. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | 0.908 |
| ADPGK | GCK | ENSPPYP00000007509 | ENSPPYP00000019722 | ADPGK isoform 4. | Phosphotransferase. | 0.955 |
| ADPGK | GPI | ENSPPYP00000007509 | ENSPPYP00000011012 | ADPGK isoform 4. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.984 |
| ADPGK | HK1 | ENSPPYP00000007509 | ENSPPYP00000002765 | ADPGK isoform 4. | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine (By similarity). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor f [...] | 0.920 |
| ADPGK | HK2 | ENSPPYP00000007509 | ENSPPYP00000013670 | ADPGK isoform 4. | HK2 isoform 1. | 0.920 |
| ADPGK | HK3 | ENSPPYP00000007509 | ENSPPYP00000017995 | ADPGK isoform 4. | HK3 isoform 2. | 0.920 |
| ADPGK | HKDC1 | ENSPPYP00000007509 | ENSPPYP00000002767 | ADPGK isoform 4. | Hexokinase domain containing 1. | 0.920 |
| ADPGK | PGM1 | ENSPPYP00000007509 | ENSPPYP00000024038 | ADPGK isoform 4. | Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. | 0.907 |
| G6PC2 | ADPGK | ENSPPYP00000014406 | ENSPPYP00000007509 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | ADPGK isoform 4. | 0.905 |
| G6PC2 | GALM | ENSPPYP00000014406 | ENSPPYP00000013940 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | 0.914 |
| G6PC2 | GCK | ENSPPYP00000014406 | ENSPPYP00000019722 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Phosphotransferase. | 0.970 |
| G6PC2 | GPI | ENSPPYP00000014406 | ENSPPYP00000011012 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Glucose-6-phosphate isomerase; In the cytoplasm, catalyzes the conversion of glucose-6- phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis (By similarity). Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion (By similarity). | 0.910 |
| G6PC2 | HK1 | ENSPPYP00000014406 | ENSPPYP00000002765 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Hexokinase-1; Catalyzes the phosphorylation of various hexoses, such as D- glucose, D-glucosamine, D-fructose, D-mannose and 2-deoxy-D-glucose, to hexose 6-phosphate (D-glucose 6-phosphate, D-glucosamine 6-phosphate, D-fructose 6-phosphate, D-mannose 6-phosphate and 2-deoxy-D-glucose 6- phosphate, respectively). Does not phosphorylate N-acetyl-D-glucosamine (By similarity). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (By similarity). Involved in innate immunity and inflammation by acting as a pattern recognition receptor f [...] | 0.937 |
| G6PC2 | HK2 | ENSPPYP00000014406 | ENSPPYP00000013670 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | HK2 isoform 1. | 0.936 |
| G6PC2 | HK3 | ENSPPYP00000014406 | ENSPPYP00000017995 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | HK3 isoform 2. | 0.936 |
| G6PC2 | HKDC1 | ENSPPYP00000014406 | ENSPPYP00000002767 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Hexokinase domain containing 1. | 0.936 |
| G6PC2 | LCT | ENSPPYP00000014406 | ENSPPYP00000014306 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | LCT isoform 1. | 0.907 |
| G6PC2 | PGM1 | ENSPPYP00000014406 | ENSPPYP00000024038 | Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. | Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. | 0.948 |
| GALM | ADPGK | ENSPPYP00000013940 | ENSPPYP00000007509 | Aldose 1-epimerase; Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity). | ADPGK isoform 4. | 0.908 |
