PDE1A protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

PDE1A

Phosphodiesterase. (545 aa)

Predicted Functional Partners:

CALML5

0.963

CALML3

0.963

CALML6

0.958

CALM1

0.958

CALML4

0.958

PDE1C

0.952

PDE1B

0.951

LOC100455662

0.935

AMPD2

0.923

GNAT3

0.923

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMPD2	PDE1A	ENSPPYP00000001238	ENSPPYP00000014514	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	Phosphodiesterase.	0.923
AMPD2	PDE1B	ENSPPYP00000001238	ENSPPYP00000005255	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	Phosphodiesterase.	0.923
AMPD2	PDE1C	ENSPPYP00000001238	ENSPPYP00000019798	AMP deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.	Phosphodiesterase.	0.923
CALM1	CALML3	ENSPPYP00000006891	ENSPPYP00000002383	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	CALML3 isoform 1; Belongs to the calmodulin family.	0.956
CALM1	CALML4	ENSPPYP00000006891	ENSPPYP00000007472	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.954
CALM1	CALML5	ENSPPYP00000006891	ENSPPYP00000002382	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 5.	0.955
CALM1	CALML6	ENSPPYP00000006891	ENSPPYP00000002306	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin like 6.	0.953
CALM1	LOC100455662	ENSPPYP00000006891	ENSPPYP00000020982	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Calmodulin-alpha-like.	0.900
CALM1	PDE1A	ENSPPYP00000006891	ENSPPYP00000014514	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.958
CALM1	PDE1B	ENSPPYP00000006891	ENSPPYP00000005255	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.952
CALM1	PDE1C	ENSPPYP00000006891	ENSPPYP00000019798	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	Phosphodiesterase.	0.956
CALML3	CALM1	ENSPPYP00000002383	ENSPPYP00000006891	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.956
CALML3	CALML4	ENSPPYP00000002383	ENSPPYP00000007472	CALML3 isoform 1; Belongs to the calmodulin family.	LOW QUALITY PROTEIN: calmodulin-like protein 4.	0.945
CALML3	CALML5	ENSPPYP00000002383	ENSPPYP00000002382	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin like 5.	0.949
CALML3	CALML6	ENSPPYP00000002383	ENSPPYP00000002306	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin like 6.	0.943
CALML3	LOC100455662	ENSPPYP00000002383	ENSPPYP00000020982	CALML3 isoform 1; Belongs to the calmodulin family.	Calmodulin-alpha-like.	0.918
CALML3	PDE1A	ENSPPYP00000002383	ENSPPYP00000014514	CALML3 isoform 1; Belongs to the calmodulin family.	Phosphodiesterase.	0.963
CALML3	PDE1B	ENSPPYP00000002383	ENSPPYP00000005255	CALML3 isoform 1; Belongs to the calmodulin family.	Phosphodiesterase.	0.961
CALML3	PDE1C	ENSPPYP00000002383	ENSPPYP00000019798	CALML3 isoform 1; Belongs to the calmodulin family.	Phosphodiesterase.	0.964
CALML4	CALM1	ENSPPYP00000007472	ENSPPYP00000006891	LOW QUALITY PROTEIN: calmodulin-like protein 4.	Calmodulin; Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases (By similarity). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (By similarity).	0.954