| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ALDH18A1 | ALDH4A1 | ENSPPYP00000002911 | ENSPPYP00000002085 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.988 |
| ALDH18A1 | CAD | ENSPPYP00000002911 | ENSPPYP00000014025 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | 0.801 |
| ALDH18A1 | GAD1 | ENSPPYP00000002911 | ENSPPYP00000014955 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.859 |
| ALDH18A1 | GFPT1 | ENSPPYP00000002911 | ENSPPYP00000013761 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GFPT1 isoform 1. | 0.447 |
| ALDH18A1 | GLS | ENSPPYP00000002911 | ENSPPYP00000014554 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS isoform 1. | 0.980 |
| ALDH18A1 | GLS2 | ENSPPYP00000002911 | ENSPPYP00000005314 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | GLS2 isoform 5. | 0.979 |
| ALDH18A1 | GLUD1 | ENSPPYP00000002911 | ENSPPYP00000003292 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.989 |
| ALDH18A1 | GLUD2 | ENSPPYP00000002911 | ENSPPYP00000023161 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamate dehydrogenase 2, mitochondrial. | 0.989 |
| ALDH18A1 | GLUL | ENSPPYP00000002911 | ENSPPYP00000000500 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamine synthetase. | 0.917 |
| ALDH18A1 | PPAT | ENSPPYP00000002911 | ENSPPYP00000023924 | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Amidophosphoribosyltransferase; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.538 |
| ALDH4A1 | ALDH18A1 | ENSPPYP00000002085 | ENSPPYP00000002911 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.988 |
| ALDH4A1 | GAD1 | ENSPPYP00000002085 | ENSPPYP00000014955 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.922 |
| ALDH4A1 | GLS | ENSPPYP00000002085 | ENSPPYP00000014554 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS isoform 1. | 0.916 |
| ALDH4A1 | GLS2 | ENSPPYP00000002085 | ENSPPYP00000005314 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | GLS2 isoform 5. | 0.927 |
| ALDH4A1 | GLUD1 | ENSPPYP00000002085 | ENSPPYP00000003292 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase 1; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.944 |
| ALDH4A1 | GLUD2 | ENSPPYP00000002085 | ENSPPYP00000023161 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamate dehydrogenase 2, mitochondrial. | 0.944 |
| ALDH4A1 | GLUL | ENSPPYP00000002085 | ENSPPYP00000000500 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Glutamine synthetase. | 0.930 |
| CAD | ALDH18A1 | ENSPPYP00000014025 | ENSPPYP00000002911 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Delta-1-pyrroline-5-carboxylate synthase; Bifunctional enzyme that converts glutamate to glutamate 5- semialdehyde, an intermediate in the biosynthesis of proline, ornithine and arginine; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.801 |
| CAD | GAD1 | ENSPPYP00000014025 | ENSPPYP00000014955 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | Glutamate decarboxylase 1; Catalyzes the production of GABA; Belongs to the group II decarboxylase family. | 0.829 |
| CAD | GFPT1 | ENSPPYP00000014025 | ENSPPYP00000013761 | Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase. | GFPT1 isoform 1. | 0.929 |