STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTLA4Cytotoxic T-lymphocyte associated protein 4. (223 aa)    
Predicted Functional Partners:
CD86
CD86 isoform 2.
   
 0.999
CD80
CD80 isoform 4.
   
 0.998
ICOSLG
ICOSLG isoform 1.
   
 
 0.968
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
   
 
 0.955
ICOS
ICOS isoform 1.
   
  
 0.952
LCN2
LCN2 isoform 1; Belongs to the calycin superfamily. Lipocalin family.
    
 
 0.934
PDCD1LG2
PDCD1LG2 isoform 1.
   
 
 0.911
CR201_G0052853
IGHG1 isoform 1.
   
 
 0.903
CR201_G0053558
IGKV3D-20 isoform 1.
    
 
 0.903
LGALS9
Galectin.
      
 0.879
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.