STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR1G protein-coupled receptor 1. (355 aa)    
Predicted Functional Partners:
RARRES2
Retinoic acid receptor responder protein 2; Adipocyte-secreted protein (adipokine) that regulates adipogenesis, metabolism and inflammation through activation of the chemokine-like receptor 1 (CMKLR1). Its other ligands include G protein-coupled receptor 1 (GPR1) and chemokine receptor-like 2 (CCRL2). Positively regulates adipocyte differentiation, modulates the expression of adipocyte genes involved in lipid and glucose metabolism and might play a role in angiogenesis, a process essential for the expansion of white adipose tissue. Also acts as a proinflammatory adipokine, causing an i [...]
      
 0.882
GPHA2
Glycoprotein hormone subunit alpha 2.
     
 0.819
GPR22
G protein-coupled receptor 22.
      
 0.628
NAMPT
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
      
 0.561
ZDBF2
ZDBF2 isoform 1.
      
 0.525
ARRB1
ARRB1 isoform 2.
    
 0.515
GNAO1
GNAO1 isoform 1.
    
 0.504
TAFA1
FAM19A1 isoform 1.
      
 0.465
EDN3
EDN3 isoform 1.
    
 0.456
GPHB5
Glycoprotein hormone subunit beta 5.
     
 0.420
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.