| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DDX28 | FASTKD2 | ENSPPYP00000008449 | ENSPPYP00000014655 | DDX28 isoform 1. | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | 0.908 |
| DDX28 | GRSF1 | ENSPPYP00000008449 | ENSPPYP00000016541 | DDX28 isoform 1. | GRSF1 isoform 2. | 0.563 |
| DDX28 | MTERF3 | ENSPPYP00000008449 | ENSPPYP00000021047 | DDX28 isoform 1. | mTERF3 isoform 4. | 0.853 |
| DDX28 | NGRN | ENSPPYP00000008449 | ENSPPYP00000007688 | DDX28 isoform 1. | Neugrin; Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. | 0.817 |
| DDX28 | PTCD1 | ENSPPYP00000008449 | ENSPPYP00000019470 | DDX28 isoform 1. | Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria- encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs. | 0.828 |
| DDX28 | RPUSD3 | ENSPPYP00000008449 | ENSPPYP00000015290 | DDX28 isoform 1. | RNA pseudouridine synthase D3. | 0.729 |
| DDX28 | RPUSD4 | ENSPPYP00000008449 | ENSPPYP00000004622 | DDX28 isoform 1. | RNA pseudouridine synthase D4. | 0.879 |
| DDX28 | TRUB2 | ENSPPYP00000008449 | ENSPPYP00000022020 | DDX28 isoform 1. | TRUB2 isoform 1. | 0.869 |
| DDX28 | YARS2 | ENSPPYP00000008449 | ENSPPYP00000005029 | DDX28 isoform 1. | Tyrosine--tRNA ligase. | 0.659 |
| FASTK | FASTKD2 | ENSPPYP00000020393 | ENSPPYP00000014655 | Fas activated serine/threonine kinase. | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | 0.727 |
| FASTK | GRSF1 | ENSPPYP00000020393 | ENSPPYP00000016541 | Fas activated serine/threonine kinase. | GRSF1 isoform 2. | 0.504 |
| FASTK | RPUSD4 | ENSPPYP00000020393 | ENSPPYP00000004622 | Fas activated serine/threonine kinase. | RNA pseudouridine synthase D4. | 0.421 |
| FASTKD2 | DDX28 | ENSPPYP00000014655 | ENSPPYP00000008449 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | DDX28 isoform 1. | 0.908 |
| FASTKD2 | FASTK | ENSPPYP00000014655 | ENSPPYP00000020393 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | Fas activated serine/threonine kinase. | 0.727 |
| FASTKD2 | GRSF1 | ENSPPYP00000014655 | ENSPPYP00000016541 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | GRSF1 isoform 2. | 0.743 |
| FASTKD2 | MTERF3 | ENSPPYP00000014655 | ENSPPYP00000021047 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | mTERF3 isoform 4. | 0.948 |
| FASTKD2 | NGRN | ENSPPYP00000014655 | ENSPPYP00000007688 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | Neugrin; Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system. | 0.945 |
| FASTKD2 | PTCD1 | ENSPPYP00000014655 | ENSPPYP00000019470 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria- encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs. | 0.884 |
| FASTKD2 | RPUSD3 | ENSPPYP00000014655 | ENSPPYP00000015290 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | RNA pseudouridine synthase D3. | 0.844 |
| FASTKD2 | RPUSD4 | ENSPPYP00000014655 | ENSPPYP00000004622 | FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. | RNA pseudouridine synthase D4. | 0.905 |
