FASTKD2 protein (Pongo abelii) - STRING interaction network

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FASTKD2

FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. (692 aa)

Predicted Functional Partners:

NGRN

0.914

MTERF3

0.869

TRUB2

0.860

DDX28

0.826

RPUSD4

0.756

FASTK

0.719

LRPPRC

0.600

GRSF1

0.597

PTCD1

0.585

TACO1

0.567

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DDX28	FASTKD2	ENSPPYP00000008449	ENSPPYP00000014655	DDX28 isoform 1.	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	0.826
DDX28	GRSF1	ENSPPYP00000008449	ENSPPYP00000016541	DDX28 isoform 1.	GRSF1 isoform 2.	0.608
DDX28	MTERF3	ENSPPYP00000008449	ENSPPYP00000021047	DDX28 isoform 1.	mTERF3 isoform 4.	0.725
DDX28	NGRN	ENSPPYP00000008449	ENSPPYP00000007688	DDX28 isoform 1.	Neugrin; Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.	0.554
DDX28	PTCD1	ENSPPYP00000008449	ENSPPYP00000019470	DDX28 isoform 1.	Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria- encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs.	0.426
DDX28	RPUSD4	ENSPPYP00000008449	ENSPPYP00000004622	DDX28 isoform 1.	RNA pseudouridine synthase D4.	0.760
DDX28	TRUB2	ENSPPYP00000008449	ENSPPYP00000022020	DDX28 isoform 1.	TRUB2 isoform 1.	0.646
FASTK	FASTKD2	ENSPPYP00000020393	ENSPPYP00000014655	Fas activated serine/threonine kinase.	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	0.719
FASTK	GRSF1	ENSPPYP00000020393	ENSPPYP00000016541	Fas activated serine/threonine kinase.	GRSF1 isoform 2.	0.468
FASTKD2	DDX28	ENSPPYP00000014655	ENSPPYP00000008449	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	DDX28 isoform 1.	0.826
FASTKD2	FASTK	ENSPPYP00000014655	ENSPPYP00000020393	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	Fas activated serine/threonine kinase.	0.719
FASTKD2	GRSF1	ENSPPYP00000014655	ENSPPYP00000016541	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	GRSF1 isoform 2.	0.597
FASTKD2	LRPPRC	ENSPPYP00000014655	ENSPPYP00000024772	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	LRPPRC isoform 5.	0.600
FASTKD2	MTERF3	ENSPPYP00000014655	ENSPPYP00000021047	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	mTERF3 isoform 4.	0.869
FASTKD2	NGRN	ENSPPYP00000014655	ENSPPYP00000007688	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	Neugrin; Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.	0.914
FASTKD2	PTCD1	ENSPPYP00000014655	ENSPPYP00000019470	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	Pentatricopeptide repeat-containing protein 1, mitochondrial; Mitochondrial protein implicated in negative regulation of leucine tRNA levels, as well as negative regulation of mitochondria- encoded proteins and COX activity. Affects also the 3'-processing of mitochondrial tRNAs.	0.585
FASTKD2	RPUSD4	ENSPPYP00000014655	ENSPPYP00000004622	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	RNA pseudouridine synthase D4.	0.756
FASTKD2	TACO1	ENSPPYP00000014655	ENSPPYP00000009576	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	TACO1 isoform 1.	0.567
FASTKD2	TRUB2	ENSPPYP00000014655	ENSPPYP00000022020	FAST kinase domain-containing protein 2, mitochondrial; Plays an important role in assembly of the mitochondrial large ribosomal subunit. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation.	TRUB2 isoform 1.	0.860
GRSF1	DDX28	ENSPPYP00000016541	ENSPPYP00000008449	GRSF1 isoform 2.	DDX28 isoform 1.	0.608

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