| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FZD5 | LRP6 | ENSPPYP00000014662 | ENSPPYP00000024153 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | 0.999 |
| FZD5 | RNF43 | ENSPPYP00000014662 | ENSPPYP00000009250 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | RNF43 isoform 2. | 0.992 |
| FZD5 | ROR1 | ENSPPYP00000014662 | ENSPPYP00000001486 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. | 0.971 |
| FZD5 | RYK | ENSPPYP00000014662 | ENSPPYP00000015796 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | RYK isoform 3. | 0.968 |
| FZD5 | WNT1 | ENSPPYP00000014662 | ENSPPYP00000005109 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.986 |
| FZD5 | WNT11 | ENSPPYP00000014662 | ENSPPYP00000004224 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.987 |
| FZD5 | WNT3 | ENSPPYP00000014662 | ENSPPYP00000009317 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.973 |
| FZD5 | WNT3A | ENSPPYP00000014662 | ENSPPYP00000000148 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.986 |
| FZD5 | WNT5A | ENSPPYP00000014662 | ENSPPYP00000015420 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.996 |
| FZD5 | WNT5B | ENSPPYP00000014662 | ENSPPYP00000004719 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.981 |
| LRP6 | FZD5 | ENSPPYP00000024153 | ENSPPYP00000014662 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.999 |
| LRP6 | RNF43 | ENSPPYP00000024153 | ENSPPYP00000009250 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | RNF43 isoform 2. | 0.732 |
| LRP6 | RYK | ENSPPYP00000024153 | ENSPPYP00000015796 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | RYK isoform 3. | 0.522 |
| LRP6 | WNT1 | ENSPPYP00000024153 | ENSPPYP00000005109 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.994 |
| LRP6 | WNT11 | ENSPPYP00000024153 | ENSPPYP00000004224 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.963 |
| LRP6 | WNT3 | ENSPPYP00000024153 | ENSPPYP00000009317 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.995 |
| LRP6 | WNT3A | ENSPPYP00000024153 | ENSPPYP00000000148 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.997 |
| LRP6 | WNT5A | ENSPPYP00000024153 | ENSPPYP00000015420 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. | 0.989 |
| LRP6 | WNT5B | ENSPPYP00000024153 | ENSPPYP00000004719 | Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. | Protein Wnt-5b; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity); Belongs to the Wnt family. | 0.980 |
| RNF43 | FZD5 | ENSPPYP00000009250 | ENSPPYP00000014662 | RNF43 isoform 2. | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. | 0.992 |
