PTH2R protein (Pongo abelii) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Genomic Predictions

gene neighborhood

gene co-occurrence

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Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CR201_G0033084	GNB1	ENSPPYP00000014891	ENSPPYP00000002307	RAMP1 isoform 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.532
CR201_G0033084	PTH1R	ENSPPYP00000014891	ENSPPYP00000015578	RAMP1 isoform 1.	Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.	0.502
CR201_G0033084	PTH2R	ENSPPYP00000014891	ENSPPYP00000014671	RAMP1 isoform 1.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.488
CR201_G0033084	RAMP3	ENSPPYP00000014891	ENSPPYP00000019704	RAMP1 isoform 1.	Receptor activity modifying protein 3.	0.573
CRH	GNB1	ENSPPYP00000020903	ENSPPYP00000002307	CRH isoform 1.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.581
CRH	PTH1R	ENSPPYP00000020903	ENSPPYP00000015578	CRH isoform 1.	Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.	0.516
CRH	PTH2R	ENSPPYP00000020903	ENSPPYP00000014671	CRH isoform 1.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.516
FZD5	GNB1	ENSPPYP00000014662	ENSPPYP00000002307	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.436
FZD5	PTH2R	ENSPPYP00000014662	ENSPPYP00000014671	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.486
GNB1	CR201_G0033084	ENSPPYP00000002307	ENSPPYP00000014891	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	RAMP1 isoform 1.	0.532
GNB1	CRH	ENSPPYP00000002307	ENSPPYP00000020903	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	CRH isoform 1.	0.581
GNB1	FZD5	ENSPPYP00000002307	ENSPPYP00000014662	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family.	0.436
GNB1	PTH	ENSPPYP00000002307	ENSPPYP00000003984	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	0.612
GNB1	PTH1R	ENSPPYP00000002307	ENSPPYP00000015578	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.	0.975
GNB1	PTH2	ENSPPYP00000002307	ENSPPYP00000011471	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	PTH2 isoform 1.	0.532
GNB1	PTH2R	ENSPPYP00000002307	ENSPPYP00000014671	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.762
GNB1	RAMP3	ENSPPYP00000002307	ENSPPYP00000019704	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	Receptor activity modifying protein 3.	0.829
PEX7	PTH1R	ENSPPYP00000019078	ENSPPYP00000015578	Peroxisomal biogenesis factor 7.	Parathyroid hormone/parathyroid hormone-related peptide receptor; Receptor for parathyroid hormone and for parathyroid hormone- related peptide. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Belongs to the G-protein coupled receptor 2 family.	0.617
PEX7	PTH2R	ENSPPYP00000019078	ENSPPYP00000014671	Peroxisomal biogenesis factor 7.	Parathyroid hormone 2 receptor; Belongs to the G-protein coupled receptor 2 family.	0.483
PTH	GNB1	ENSPPYP00000003984	ENSPPYP00000002307	Parathyroid hormone; PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion; Belongs to the parathyroid hormone family.	Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.	0.612