STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP2Microtubule-associated protein. (1770 aa)    
Predicted Functional Partners:
SYP
SYP isoform 1.
   
  
 0.729
PRKAR2B
PRKAR2B isoform 1.
   
 
 0.696
GFAP
Glial fibrillary acidic protein; GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
   
 
 0.647
DLG4
DLG4 isoform 3; Belongs to the MAGUK family.
   
 0.642
CASP3
CASP3 isoform 1; Belongs to the peptidase C14A family.
    
 0.632
NEFL
Neurofilament light polypeptide; Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.
   
 
 0.617
RBFOX3
RBFOX3 isoform 4.
   
 
 0.613
CDK5
Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.
    
 
 0.600
SYN1
SYN1 isoform 2.
   
 
 0.598
MBP
MBP isoform 10.
   
  
 0.595
Your Current Organism:
Pongo abelii
NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.