CNPPD1 protein (Pongo abelii) - STRING interaction network

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CNPPD1

Protein CNPPD1. (410 aa)

Predicted Functional Partners:

LIG4

0.615

XRCC5

0.598

XRCC6

0.570

PCNP

0.408

TMEM65

0.405

Your Current Organism:

Pongo abelii

NCBI taxonomy Id: 9601
Other names: Orang-utan, Orangutan, P. abelii, Pongo pygmaeus abeli, Pongo pygmaeus abelii, Sumatran orangutan, orang utan

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CNPPD1	LIG4	ENSPPYP00000014744	ENSPPYP00000006314	Protein CNPPD1.	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	0.615
CNPPD1	PCNP	ENSPPYP00000014744	ENSPPYP00000015195	Protein CNPPD1.	PEST proteolytic signal-containing nuclear protein; May be involved in cell cycle regulation.	0.408
CNPPD1	TMEM65	ENSPPYP00000014744	ENSPPYP00000021166	Protein CNPPD1.	TMEM65 isoform 1.	0.405
CNPPD1	XRCC5	ENSPPYP00000014744	ENSPPYP00000014697	Protein CNPPD1.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.598
CNPPD1	XRCC6	ENSPPYP00000014744	ENSPPYP00000013253	Protein CNPPD1.	XRCC6 isoform 3.	0.570
LIG4	CNPPD1	ENSPPYP00000006314	ENSPPYP00000014744	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	Protein CNPPD1.	0.615
LIG4	XRCC5	ENSPPYP00000006314	ENSPPYP00000014697	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.986
LIG4	XRCC6	ENSPPYP00000006314	ENSPPYP00000013253	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	XRCC6 isoform 3.	0.954
PCNP	CNPPD1	ENSPPYP00000015195	ENSPPYP00000014744	PEST proteolytic signal-containing nuclear protein; May be involved in cell cycle regulation.	Protein CNPPD1.	0.408
TMEM65	CNPPD1	ENSPPYP00000021166	ENSPPYP00000014744	TMEM65 isoform 1.	Protein CNPPD1.	0.405
XRCC5	CNPPD1	ENSPPYP00000014697	ENSPPYP00000014744	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	Protein CNPPD1.	0.598
XRCC5	LIG4	ENSPPYP00000014697	ENSPPYP00000006314	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	0.986
XRCC5	XRCC6	ENSPPYP00000014697	ENSPPYP00000013253	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	XRCC6 isoform 3.	0.997
XRCC6	CNPPD1	ENSPPYP00000013253	ENSPPYP00000014744	XRCC6 isoform 3.	Protein CNPPD1.	0.570
XRCC6	LIG4	ENSPPYP00000013253	ENSPPYP00000006314	XRCC6 isoform 3.	DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.	0.954
XRCC6	XRCC5	ENSPPYP00000013253	ENSPPYP00000014697	XRCC6 isoform 3.	X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family.	0.997